Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.
Maternal immune responses during mice gestation led to a hyperactive population of innate-like immune cells in offspring that contributed to altered lung composition and function.
A more realistic model of the mucus layer that lines the lungs and gut could provide important insights into the function of this critical defensive barrier.