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physiology

3 days ago | 2 min read

Why Do Humans Have an Appendix?

Long believed to be purely vestigial, this troublesome organ may play an important role in gut and immune function.
A human torso with the large bowel depicted in blue and the appendix in red.
3D rendering of a transparent human torso to show the lungs and bronchiole structures in them.
Aug 20, 2024 | 4 min read

Prenatal Inflammation Makes Mice Susceptible to Asthma

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Amino acid sequence presented on a computer screen as one-letter codes.
Revving the Motor: Full-Length Protein Sequencing with Nanopore Technology
Nathan Ni, PhD | Aug 12, 2024 | 4 min read
Jeff Nivala develops nanopore-based sequencing techniques to help advance proteomics. 
Confocal image of a developing embryo with blue-labeled nuclei and orange stained edges.
Unraveling the Complex Mysteries of Embryonic Beginnings
Shelby Bradford, PhD | Jul 4, 2024 | 6 min read
Magdalena Zernicka-Goetz followed the aesthetic allure of the embryo to better understand the start of development.
Modeling the Intestines with Mini Guts
Modeling the Intestines with Mini Guts
The Scientist Staff | 1 min read
In this webinar, Arthur Beyder and Melanie Maya Kaelberer will discuss how scientists use intestinal organoids, also known as mini guts, to explore the digestive system in health and disease.
On the left, a diagram of a fetus and placenta inside the abdomen of a pregnant person, on the right, a pink mitochondrion.
Mitochondria: The Powerhouse of the Placenta
Hannah Thomasy, PhD | Jul 1, 2024 | 2 min read
Scientists seek citizens’ help to survey placental mitochondria in complicated and healthy pregnancies.
A mouse stands behind a toy table with two pieces of food on it.
A Protein-Sensing Molecular Switch Alters Facial Features
Shelby Bradford, PhD | Jun 24, 2024 | 3 min read
The mTORC1 signaling pathway senses nutritional information and influences craniofacial development in mice.
Image showing the legs of multiple people running in the street. 
Another Reason to Challenge Yourself at the Gym
Alara Tuncer | 4 min read
In a chronic stress model, challenging exercise reduced anxiety by activating a three-neuron loop across brain regions.  
Microscopy photo of a dissected fly ovary with mature oocytes visible as dark ovals.
How Nutrition Regulates Ovulation
Shelby Bradford, PhD | Jun 19, 2024 | 4 min read
Fly fat tissue senses nutritional status through a stress response pathway to control reproductive activities.
A baby cries
Why are Tears Important?
Mariella Bodemeier Loayza Careaga, PhD | Jun 3, 2024 | 2 min read
Human tears are a blend of elements that lubricate and protect the human eye.
istock
Natural Trip: Endogenous Psychedelics and Human Physiology
The Scientist | 1 min read
Researchers explore the trippy science behind natural hallucinogens in humans. 
The heart sections on the left present defects while the hearts on the right do not show defects. 
Genetic Signatures of a Defective Heart
Mariella Bodemeier Loayza Careaga, PhD | May 14, 2024 | 4 min read
In a mouse model of Down syndrome, three copies of a gene encoding a kinase contributed to congenital heart defects.
A developing embryo with DNA labeled blue, cell boundaries labeled pink, and certain cells fluorescing green.
The First Two Cells in a Human Embryo Contribute Disproportionately to Fetal Development
Shelby Bradford, PhD | May 13, 2024 | 4 min read
A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus.
Illuminating Organs with Organoids
Illuminating Organs with Organoids
The Scientist | 1 min read
In this webinar, Benjamin Freedman talks about the importance of organoids in modeling organ function and disease.
An artistic illustration of the female reproductive system.
Outsmarting Ovarian Cancer
Mariella Bodemeier Loayza Careaga, PhD | May 8, 2024 | 4 min read
Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process. 
An antenna-like cellular structure emerges from the surface of a human pancreatic islet cell. The surface of the cell is covered with small structures called microvilli.
The Shape of Cilia
Mariella Bodemeier Loayza Careaga, PhD | May 1, 2024 | 2 min read
Three dimensional images of human pancreatic islet cells provide an unprecedented view of the enigmatic primary cilia.
Discover How CF® Dyes Let Scientists Delve Deeper into Biological Phenomena
CF® Dyes: Clearer Fluorescent Results
Biotium | 1 min read
CF®  Dyes combine pegylation and sulfonation to create fluorescent dyes with better signal intensity, more solubility, and superior specificity.
Soybeans growing against a black background.
How Do Plants Know Which Way is Up?
Hannah Thomasy, PhD | May 1, 2024 | 2 min read
Despite centuries of study, scientists still make new discoveries about the mechanisms of gravitropism.
3D wireframe conceptual image of a human head with a white netting overlay on a purple background.
Interstitium: A Network of Living Spaces Supports Anatomical Interconnectedness
Iris Kulbatski, PhD | Apr 26, 2024 | 6 min read
What researchers once regarded as a byproduct of biology may hold the key to understanding health and disease.
Spatial Multiomics Reveal Microbiome-Linked T Cell Modulations in Human Graft-Versus-Host Disease
Spatial Multiomics Reveal Microbiome-Linked T Cell Modulations in Human Graft-Versus-Host Disease
The Scientist | 1 min read
In this webinar, Benton Berigan will highlight the value of combining multimodal data, including spatial information, to understand complex immunological processes.
Unveiling the Mysteries of Hibernation and Torpor
Mariella Bodemeier Loayza Careaga, PhD | Apr 1, 2024 | 2 min read
Neuroscientist Siniša Hrvatin explores how animals initiate and regulate states of dormancy.
A pregnant woman blowing her nose.
Viral Immune Responses Suppress a Gestational Hormone
Shelby Bradford, PhD | Mar 25, 2024 | 4 min read
Influenza infection activates a pathway that leads to a detrimental drop in progesterone during pregnancy in mice.
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