Following decades of being called “the powerhouse of the cell,” researchers recently proposed a new description that reflects the multifaceted roles of mitochondria.
In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related neurodegenerative diseases.
Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease.