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A syringe inserted into a vial of vaccine.
Engineered Yeast Brew a Vaccine Adjuvant 
Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.
Engineered Yeast Brew a Vaccine Adjuvant 
Engineered Yeast Brew a Vaccine Adjuvant 

Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.

Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.

yeast

Yeast art of <em >The Scientist</em>&rsquo;s logo.
When Masterpieces Arise from Yeast
Laura Tran, PhD | Jun 17, 2024 | 6 min read
Jef Boeke and his team create intricate works of art on Petri dishes using a palette of yeast paints.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Dead shark on concrete
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient
Natalia Mesa, PhD | Feb 22, 2023 | 3 min read
Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.
Lock and key illustration
Novel Yeast-Assembly Technique Yields Living Materials
Natalia Mesa, PhD | Nov 23, 2022 | 3 min read
Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.
Illustration of blue and gray amino acids loosely forming protein
Fungal Cold Adaptation Linked to Protein Structure Changes: Study
Patience Asanga | Sep 20, 2022 | 4 min read
Environmental pressure seems to spawn changes in the intrinsically disordered regions of enzymes in polar yeasts, allowing them to adapt to extreme cold.
A photograph of Christine Guthrie and Hiten Madhani
RNA Pioneer Christine Guthrie Dies at 77
Amanda Heidt | Sep 1, 2022 | 5 min read
Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.
orange tiny frog
Caught on Camera
The Scientist | Aug 15, 2022 | 2 min read
See some of the coolest images recently featured by The Scientist
Microscopic view of Candida albicans
Science Snapshot: Taming the Fungus Amongus
Lisa Winter | Jun 8, 2022 | 1 min read
Human mucus contains glycans that could one day treat harmful Candida albicans infections.
A micrograph of the prion-like state of a protein called Pus4
Protein Mediates Non-Genetic Inheritance of Growth Strategies
Catherine Offord | Jan 4, 2022 | 2 min read
An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.
Neuro collage
Our Favorite Neuroscience Stories of 2021
Chloe Tenn | Dec 29, 2021 | 4 min read
From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021 | 3 min read
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Fruit flies in a vial
Accurate Protein Production Promotes Longevity
Ruth Williams | Sep 15, 2021 | 3 min read
Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.
Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021 | 1 min read
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
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Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Roni Dengler, PhD | Aug 16, 2021 | 3 min read
Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.
a white menstrual pad with pink and yellow spotting
Threads Embedded in Pads and Tampons Can Diagnose Yeast Infection
Emma Yasinski | Jun 15, 2021 | 3 min read
The material turns bright pink when it comes in contact with an enzyme produced by the fungus Candida albicans.
Humans Domesticated Yeast Through Bread-Making: Study
Max Kozlov | Dec 11, 2020 | 4 min read
Over centuries of cultivating Saccharomyces cerevisiae to make dough, bakers have put selective pressure on the species, causing it to diverge into two distinct groups, according to the authors.
Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method
Ruth Williams | May 6, 2020 | 4 min read
The use of yeast artificial chromosomes has enabled the rapid genetic reconstruction of the novel coronavirus.
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