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A composite image showing raw capture of endosomes using lattice light sheet microscopy, represented by teal and purple spheres, and detection and tracking of endosomal movement, represented by teal and purple lines.
Changing Identities: Imaging Endosomal Maturation
Harrison York combines microscopy and machine learning to visualize and characterize how endosomes regulate intracellular mechanisms. 
Changing Identities: Imaging Endosomal Maturation
Changing Identities: Imaging Endosomal Maturation

Harrison York combines microscopy and machine learning to visualize and characterize how endosomes regulate intracellular mechanisms. 

Harrison York combines microscopy and machine learning to visualize and characterize how endosomes regulate intracellular mechanisms. 

vesicles

A microscopy image stained for different cell populations in breast tumors.
Cancer Cells Give Orders
Holly Barker, PhD | Apr 23, 2024 | 4 min read
Cancer-supporting cells control their neighbors’ behavior using an often-overlooked protein delivery system. 
Engineered RNA Export From Living Cells
Danielle Gerhard, PhD | Dec 1, 2023 | 1 min read
A nondestructive approach for packaging, exporting, and delivering RNA provides a glimpse into the dynamic lives of cells.
Extracellular vesicle cross-section showing internal and external components
Exploring Extracellular Vesicles: Biomarkers and Beyond
Biotium | 1 min read
Advances in molecular profiling tools and techniques help scientists detect and identify extracellular vesicle markers.
the facade of a building. crisscrossed white walls intersect sets of four black windows in a lattice structure, with a cloudless blue sky in the background.
Exosome Scientist Douglas Taylor Stole and Mislabeled Images: Report
Katherine Irving | Nov 23, 2022 | 2 min read
Taylor, formerly of the University of Louisville, is known for his discovery of and research on tumor-secreted exosomes.  
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.
Extracellular Vesicles: Applications and Potential
Beckman Coulter Life Sciences | 1 min read
Explore why extracellular vesicles are attractive candidates for new therapeutic approaches.
Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021 | 3 min read
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018 | 2 min read
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Neurons Use Virus-Like Proteins to Transmit Information
Diana Kwon | Jan 15, 2018 | 2 min read
In mice and flies, the Arc protein forms capsids and carries genetic information.
Macrophages Physically Relay Signals Between Cell Types
Catherine Offord | May 1, 2017 | 3 min read
Time-lapse imaging shows the immune cells transferring chemical signals during pigment pattern formation in developing zebrafish.
Infographic: How the Zebrafish Got Its Stripes
Catherine Offord | Apr 30, 2017 | 1 min read
Immune cells called macrophages shuttle cellular messages in the skin.
Neuron Signaling Persists, Faintly, Even When Key Presynaptic Proteins Are Absent
Ben Andrew Henry | Nov 1, 2016 | 2 min read
Results from experiments in mice revise a long-held hypothesis that certain protein scaffolds are needed for synaptic activity.
Palade Particles, 1955
Kerry Grens | Feb 1, 2014 | 2 min read
Electron microscopy led to the first identification of what would later be known as ribosomes.
Palade and His Particles
Kerry Grens | Jan 31, 2014 | 1 min read
Nobel Laureate Christian de Duve discusses the impact of George Palade’s work on ribosomes.
Microbes Expel Swarms of Vesicles
Kerry Grens | Jan 10, 2014 | 2 min read
Scientists present the first evidence that marine cyanobacteria release vesicles—billions and billions of vesicles.
Week in Review: October 7–11
Jef Akst | Oct 11, 2013 | 5 min read
Nobels awarded for vesicle trafficking and computational chemistry; building 3-D microbial communities; mislabeled microbes cause retractions
Vesicle Trafficking Trio Wins Nobel
Kerry Grens | Oct 7, 2013 | 2 min read
James Rothman, Randy Schekman, and Thomas Südhof share Nobel Prize in Medicine or Physiology.  
SNAREs at the Synapse
Megan Scudellari | Jul 1, 2012 | 3 min read
Using tiny lipid discs, scientists resolve contradictory evidence about how many proteins are required for neurotransmitter release.
Cancer Exosomes Promote Metastasis
Jef Akst | May 29, 2012 | 1 min read
Vesicles released by melanoma cells stimulate pro-metastasis behaviors in bone marrow cells.
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