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A syringe inserted into a vial of vaccine.
Engineered Yeast Brew a Vaccine Adjuvant 
Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.
Engineered Yeast Brew a Vaccine Adjuvant 
Engineered Yeast Brew a Vaccine Adjuvant 

Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.

Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.

vaccine design

Dead shark on concrete
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient
Natalia Mesa, PhD | Feb 22, 2023 | 3 min read
Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.
RSV vaccine design concept art
RSV Vaccines That Work?
Rachael Moeller Gorman | Feb 16, 2023 | 10+ min read
Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.
Learn about the latest research on optimal vaccine-induced immune responses
Modulating the Immune Response to Vaccines
The Scientist | 1 min read
Researchers uncover innovative natural approaches to fine-tune immunity from vaccination.
Fluorescence image in purple and green of lymph node
Targeting Antigen “Sanctuary” in Lymph Nodes Could Make Vaccines Better
Natalia Mesa, PhD | Feb 10, 2023 | 3 min read
Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.
a newly hatched mosquito sits on top of water, with its discarded cocoon floating below
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
Katherine Irving | Jan 20, 2023 | 4 min read
A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.
3D medical illustration of peripheral blood cells: a lymphocyte (left) and a monocyte (right) surrounded by red blood cells.
PBMCs: Mononucleated and Multipurposed
Deanna MacNeil, PhD | 4 min read
Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine.
person in white jacket putting bandaid on arm of child
Can We Predict How Well Someone Will Respond to a Vaccine?
Natalia Mesa, PhD | Nov 14, 2022 | 7 min read
Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 
A vial labeled “RSV vaccine” on a reflective surface next to a syringe.
After Decades of Delays, RSV Vaccines Show Promise in Early Data 
Dan Robitzski | Nov 1, 2022 | 3 min read
Both Pfizer and GSK have shared preliminary data suggesting that their experimental vaccines can protect older adults and newborn infants from the virus.
iStock
The Scientist Speaks - To Conserve and Protect: The Quest for Universal Vaccines
Niki Spahich, PhD | 1 min read
Patrick Wilson discusses the challenges in designing universal vaccines and his work developing one for influenza.
several blue office chairs sit empty in a carpeted room, with a paper sign saying "Vaccination centre welcome" pasted on the white wall above. 
Is a Winter COVID-19 Case Surge Coming?
Katherine Irving | Oct 17, 2022 | 3 min read
Low booster rates and immune-evading SARS-CoV-2 variants could spell bad news, experts say. 
A person in a white shirt activates a nasal spray
Oxford-AstraZeneca Nasal COVID-19 Vaccine Falters in Clinical Trial
Dan Robitzski | Oct 11, 2022 | 2 min read
Researchers say they’re abandoning the project in its current form—one of several that aims to induce what’s known as mucosal immunity against SARS-CoV-2.
A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
commercial airplane<br><br>
Air France Announces End to Research Monkey Transport
Andy Carstens | Jul 6, 2022 | 2 min read
The shift is likely to add to an ongoing shortage of primates used in labs, which could slow progress in future COVID-19 vaccine development and other areas.
Vaccine illustration&nbsp;
Infographic: Inducing Active Immunity Against Opioid Overdose
Tori Rodriguez | Jun 13, 2022 | 3 min read
How scientists aim to induce an immune response against addictive drugs
Illustration of a syringe with a person falling out of a bottle of pills
Opioid Vaccines as a Tool to Stem Overdose Deaths
Tori Rodriguez | Jun 13, 2022 | 10+ min read
Researchers are turning to the immune system for help in treating addiction and preventing overdose.
Spraying spray bottle
Nasal Vaccines Are Commercially High Risk, Perhaps High Reward
Jef Akst | Jun 13, 2022 | 10+ min read
Dozens of intranasally delivered vaccines targeting SARS-CoV-2 are in development. Could they pave the way for widespread nasal vaccination in the future?
Illustration showing rod-shaped Mycobacterium tuberculosis bacteria in the lungs of a person with tuberculosis
Delayed T cell Response Allows Tuberculosis to Gain Foothold in Monkeys
Anna Napolitano, PhD | Jun 1, 2022 | 5 min read
The results could help guide the design of new vaccines for the disease.
Man in personal protective equipment (glasses, gloves, cap, and coat) watching plants go through a piece of machinery.
Canada Approves World’s First Plant-Based COVID-19 Vaccine
Natalia Mesa, PhD | Feb 25, 2022 | 2 min read
Canada has ordered 76 million doses of Covifenz, the main ingredient of which was manufactured in the leaves of a tobacco relative.
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