tRNA

Synthetic biologists repurposed rarely used codons to install novel amino acids into proteins and expand the capabilities of protein engineering.

Self-contained synthetic E. coli resistant to viral infection could prove invaluable to the biotechnology industry by increasing product consistency and reducing safety concerns. 

A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.

Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

Neurologically important noncoding RNAs come in many shapes and sizes.

The biophysicist shared the 1989 Prize in Chemistry for discovering RNA’s catalytic properties.

Transfer RNA fragments prevent jumping genes from hopping around in the mouse embryo, when histone methylation can’t do the job.

Researchers apply in vitro evolution to generate an RNA enzyme capable of copying and amplifying RNA.

Researchers find that a type of neurodegeneration in mice is linked to ribosomal stalling during protein translation in the brain.

Scientists discover a broad spectrum of alternatively spliced human protein variants within a well-studied family of genes.  

Rewriting the genetic code can lead to a better understanding of how living cells work, and spawn new biotechnological applications.

Disruptions in the interaction between nuclear and mitochondrial DNA can lead to deficiencies in the mitochondrial energy-generating process, affecting fitness.

Regenesis and The Half-Life of Facts