single-cell analysis

Flow-based methods allow researchers to collect multiparameter data from individual cells in their samples, but the fate of samples depends on the instrument.

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 

Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

There is only one week remaining to submit your new product to vie for a coveted spot in The Scientist’s 2022 competition.

Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.

Analyses from single-cell sequencing datasets support the idea that COVID-19 is not just a respiratory disease but an illness that can affect multiple organs.

Systems biologist Steven Wiley says advancements in two areas—single-cell biology and CRISPR—are poised to transform research.  

A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.

Researchers track which genes are active in the polyp during successive cell states.

An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).