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hCINAP Protein Key to Cellular Senescence: Study
The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.
hCINAP Protein Key to Cellular Senescence: Study
hCINAP Protein Key to Cellular Senescence: Study

The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.

The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.

senescence

Conceptual image of hair loss showing trees in the shape of a human head at various seasonal stages of shedding their leaves.
Islands of Knowledge: Hairy Skin Moles Make Their Mark
Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read
Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.
A 3D medical illustration of a human heart with a cardiogram in the foreground and a blue background that includes DNA helices.
Connecting the Complexities of Heart Failure and Aging
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers learned how IGFBP7, a senescence signaling protein and biomarker, promotes cardiac remodeling and cellular aging.
Teaching Old Drugs New Tricks
Teaching Old Drugs New Tricks
The Scientist Staff | 1 min read
Learn how scientists develop antibody drug conjugates as therapies for age-related diseases.   
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
3D rendered images of three T cell
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa, PhD | Sep 16, 2022 | 5 min read
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
Aging and Cancer
Aging and Cancer
Rebecca Roberts, PhD | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms. 
Photograph looking up a tree trunk
Contrary to Common Belief, Some Older Trees Make Fewer Seeds
Annie Melchor | Nov 1, 2021 | 2 min read
An analysis of more than half a million trees reveals that many species begin to taper off seed production once they hit a certain size.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
Infographic: How Does Cell Senescence Drive Aging and Disease?
Katarina Zimmer | Mar 1, 2020 | 4 min read
The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.
Ginkgo’s Extreme Longevity Credited to Immune System
Lisa Winter | Jan 15, 2020 | 2 min read
Genes related to the immune system stay active throughout the tree’s life.
Cellular Senescence in Astrocytes May Play Central Role in Parkinsonā€™s Disease
Katarina Zimmer | Jan 24, 2018 | 4 min read
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  
Trump Picks National Cancer Institute Director
Kerry Grens | Jun 12, 2017 | 1 min read
Ned Sharpless currently leads the cancer center at the University of North Carolina, Chapel Hill.
Controlled Splicing Extends Life Span in Roundworms
Ruth Williams | Dec 6, 2016 | 3 min read
Increasing the expression of an RNA splicing factor mimics dietary restriction, prolonging life in nematodes. 
Aging Shrinks Chromosomes
Ruth Williams | Feb 5, 2016 | 3 min read
A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.
Age-Old Questions
Mary Beth Aberlin | Mar 1, 2015 | 3 min read
How do we age, and can we slow it down?
Obesity-Cancer Link Detailed
Chris Palmer | Jun 26, 2013 | 3 min read
Obesity drives an alteration of the gut microbiome, leading to the secretion of metabolites associated with the development of liver cancer.
A New Model of Yeast Aging
Hannah Waters | Nov 23, 2011 | 4 min read
New findings challenge long-held views about the mechanism yeast cells use to live forever.
Old Cells Advance Aging
Tia Ghose | Nov 2, 2011 | 2 min read
By selectively killing senescent cells, researchers can slow the decline of health in aging mice.
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