Salmonella

In Salmonella, two seemingly similar antibiotic survival strategies result from very different molecular mechanisms.

Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.

Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.

To manipulate the microbiome, researchers engineered a CRISPR delivery system that precisely targets bacteria in the mouse gut.

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

In mice, a kind of immune memory appears to protect the cells against future harm, a finding that could provide insight into treatments for irritable bowel syndrome and other inflammatory digestive conditions.

Recent studies describe how resident microbiota appear to outcompete unwelcome visitors, either with superior weaponry or by guzzling up local resources.  

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.

The Salk Institute researcher was one of the first to show that killing a pathogen isn’t the only way to survive an infection.

NASA’s vegetable production system, known as Veggie, may help pave the way for more sophisticated systems that could supplement astronauts’ diets during long trips to space.

Scientists identify microbes in mice that help defend against Salmonella.

Scientists find varied microbiota among the same strain of mice from four vendors—and that variability affects their susceptibility to infection.

Cryo-electron tomography reveals how Salmonella sets up physical interactions with host cells.

Viruses within Salmonella rapidly spread genes throughout the bacterial population during a gut infection, scientists show.

Researchers employ an engineered microbe to destroy tumor cells in mice.

Scientists identify a barrier in mice between the intestine and its blood supply, and suggest how Salmonella sneaks through it.

Meet the peptide-covered microcantilever device capable of differentiating subtypes of Salmonella.

Salmonella enterica can exploit a standard immune response in mice to promote its own growth.