Alejandra Manjarrez, PhD | May 24, 2021 | 4 min read
After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.
Microbes that dwell in nutrient-poor waters use a photopigment called retinal to harvest energy from sunshine at levels at least equal to those stored by chlorophyll-based systems.
The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light.