reactive oxygen species

When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.

The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.

Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.

Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.

Researchers study how oxygen around an embryo helps shape the way feet and digits form in amphibians and chickens.

At magnetic field intensities somewhat above that of Earth, stem cell proliferation shifts gears.

The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.

Even if people exercise, hydrogen peroxide and other reactive molecules continue to accumulate in the tissues.

In zebrafish, some amount of reactive oxygen species is required for normal development.

The chemist examined the role of activated oxygen molecules in biological processes.

Molecular probes for imaging in live animals

Mouse experiments indicate that, contrary to observations in pregnant women, reactive oxygen species contribute to normal placental development.

Certain diabetes drugs with antioxidant properties promote metastasis in mice with existing tumors, researchers report.

Deficiency in a protein called pejvakin makes inner ear cells more vulnerable to sound, unable to brace themselves against oxidative stress stimulated by noise. 

Two compounds boost the ability of melanoma cells to invade other tissues in mice, providing additional evidence that antioxidants can be beneficial to malignant cells as well as healthy ones.

Reactive oxygen species have opposing effects on roundworm longevity depending on whether these molecules are in the mitochondria or the cytoplasm.

György Hajnóczky uncovers the chemical and physical strategies by which mitochondria communicate and function within a cell.