Expanding the Genetic Alphabet
Expanding the Genetic Alphabet
Synthetic biologists repurposed rarely used codons to install novel amino acids into proteins and expand the capabilities of protein engineering.
Synthetic biologists repurposed rarely used codons to install novel amino acids into proteins and expand the capabilities of protein engineering.
protein engineering
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Now AI Can Be Used to Design New Proteins
Kamal Nahas, PhD | Mar 3, 2023 | 4 min read
Machine learning can be harnessed to synthesize artificial light-bearing enzymes that actually work in cells.
Post-Translational Control: The Next Step in Synthetic Circuits
Deanna MacNeil, PhD | Feb 27, 2023 | 3 min read
Researchers engineer a protease-mediated post-translational path faster than gene switches for processes that need to happen quickly, such as insulin release.
Enhancing Protein Engineering: Site Saturation Variant Libraries
Twist Bioscience | Feb 22, 2023 | 1 min read
Scientists compared protein engineering with a synthetic library versus error-prone PCR to achieve better variant representation and simpler validation.
Characterizing Protein Oligomerization Dynamics with Automated Mass Photometry
The Scientist | Sep 30, 2022 | 1 min read
In this webinar, Gareth Rogers will discuss how mass photometry and automated mass photometry work using case studies that evaluated the oligomeric status of proteins.
Introducing Custom Recombinant Expression Services at the Cutting Edge of Biomolecular Engineering
The Scientist and Sino Biological | Mar 24, 2022 | 3 min read
A turnkey CRO service platform for recombinant protein and antibody expression and production
Promoting Stem Cell Growth and Self-Renewal In Vitro
The Scientist Creative Services Team in collaboration with MilliporeSigma | Feb 19, 2021 | 2 min read
An engineered laminin substrate facilitates high-quality human stem cell cultures.
Chemogenetics Method Uses Anti-Smoking Drug to Control Cells
Ruth Williams | Mar 14, 2019 | 3 min read
A new set of engineered receptors responds to an FDA-approved drug to provide the most potent chemogenetic toolkit to date.
Six-Letter DNA Alphabet Produces Proteins in Cells
Ruth Williams | Nov 29, 2017 | 4 min read
Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.
Bioengineering Professor, Students Accused of Fraud
Kerry Grens | Sep 30, 2017 | 1 min read
Virginia Tech’s Yiheng Percival Zhang was arrested for misusing grant funds from the federal government.
Chemical Engineer Wins Millennium Technology Prize
Tanya Lewis | May 25, 2016 | 1 min read
Caltech’s Frances Arnold is honored for her work on directed evolution.
Spinning Recombinant Spider Silk
Jenny Rood | Mar 6, 2015 | 1 min read
Scientists engineer E. coli to produce artificial spider silk.
Grab ’n’ Glow
Ruth Williams | Jan 1, 2015 | 2 min read
Engineered proteins can tether multiple fluorescent molecules to give a brighter signal—and that’s not all.
Detailing Color Vision
Ruth Williams | Dec 6, 2012 | 3 min read
Scientists engineer a spectrum of artificial pigments to understand how animals see in color.
When Zinc Fingers Miss the Mark
Tia Ghose | Aug 7, 2011 | 3 min read
Two new techniques identify how often zinc fingers nucleases cleave off-target sites.
Engineered proteins for fighting flu
Cristina Luiggi | May 14, 2011 | 3 min read
In a feat of computational biology, researchers design novel proteins capable of neutralizing a key influenza protein.