Engineering the Microbiome: CRISPR Leads the Way
Engineering the Microbiome: CRISPR Leads the Way
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
probiotics
Infographic: Engineering Microbiomes with CRISPR
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 2 min read
Researchers are using CRISPR for precise genetic manipulation of human-associated microbes as a promising avenue for improving human health.
A Probiotic to Protect Caribbean Corals
Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2023 | 2 min read
A bacterial strain from healthy corals could slow the progression and prevent transmission of the destructive stony coral tissue loss disease in the wild.
High-Fat Diet in Mice Affects Social Behavior Across Generations
Sophie Fessl, PhD | Oct 27, 2022 | 4 min read
Pups born to mice whose mothers had been fed a high-fat diet showed social deficits, a study shows.
Manipulating the Microbiome to Manage Disease
The Scientist Creative Services Team in collaboration with Tecan | May 28, 2021 | 1 min read
Cammie Lesser will discuss how she turns a probiotic into a drug-delivering machine, while Andrew Y. Koh will describe the connection between the gut microbiota and cancer immunotherapy efficacy.
LabTalk Podcast - Bugs with Drugs: Repurposing a Pathogenic Bacteria’s Weapon
The Scientist | Apr 16, 2021 | 1 min read
Cammie Lesser describes her research developing designer probiotics to deliver protein-based therapeutics to the gut.
The Infant Gut Microbiome and Probiotics that Work
Jennifer T. Smilowitz and Diana Hazard Taft | Jun 1, 2020 | 10+ min read
The gut microbiome is more malleable in the first two years after birth, allowing probiotics to make their mark. Can we exploit this to improve infants’ health?
Infographic: The Changing Infant Gut Microbiome
Jennifer T. Smilowitz and Diana Hazard Taft | Jun 1, 2020 | 3 min read
The microbial makeup of a newborn baby’s intestines has changed dramatically over the past 100 years, and we are now beginning to understand how and why this matters.
Infographic: Gut Microbes Change How Well Drugs Work
Shawna Williams | Jul 15, 2019 | 2 min read
Our resident bacteria can affect the activity of immunotherapies and other medicines in the body.
How the Microbiome Influences Drug Action
Shawna Williams | Jul 15, 2019 | 10+ min read
Through their effects on metabolism and immunity, bacteria in the gut affect whether medications will be effective for a given patient.
Probiotics’ Effects on the Microbiome Vary Widely
Abby Olena, PhD | Sep 6, 2018 | 4 min read
Experiments in mice and people find that probiotic supplements don’t consistently change the composition of the gut microbiome, and may have adverse effects after antibiotics.
Peanut Allergy Treatment Works Long Term
Jef Akst | Aug 17, 2017 | 1 min read
Four years after taking a probiotic and peanut protein for 18 months, two-thirds of children in a small clinical trial can eat peanuts with no health issues.
Next Generation: Souped-up Probiotics Pinpoint Cancer
Kate Yandell | May 28, 2015 | 3 min read
Genetically engineered commensal bacteria help researchers detect cancer metastases in mouse livers.