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A smiling woman holds a young child outside in the park.
A Stranger to Oneself: The Mystery of Fetal Microchimerism
During pregnancy, fetal cells invade maternal tissues and can persist for decades, but the effects of these non-self cells remain largely obscure.
A Stranger to Oneself: The Mystery of Fetal Microchimerism
A Stranger to Oneself: The Mystery of Fetal Microchimerism

During pregnancy, fetal cells invade maternal tissues and can persist for decades, but the effects of these non-self cells remain largely obscure.

During pregnancy, fetal cells invade maternal tissues and can persist for decades, but the effects of these non-self cells remain largely obscure.

pregnancy

On the left, a diagram of a fetus and placenta inside the abdomen of a pregnant person, on the right, a pink mitochondrion.
Mitochondria: The Powerhouse of the Placenta
Hannah Thomasy, PhD | Jul 1, 2024 | 2 min read
Scientists seek citizens’ help to survey placental mitochondria in complicated and healthy pregnancies.
A white and tan mother rat watches over several rat pups. 
Babies on the Brain
Hannah Thomasy, PhD | Apr 1, 2024 | 2 min read
In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.
Cell-Free DNA as Disease Biomarkers
Cell-Free DNA as Disease Biomarkers
The Scientist | 1 min read
In this webinar, Stella Goulopoulou and Iwijn de Vlaminck will discuss how they analyze cell-free DNA to identify biomarkers of various diseases and their complications, including preeclampsia, COVID-19, and transplant rejections.
A pregnant woman blowing her nose.
Viral Immune Responses Suppress a Gestational Hormone
Shelby Bradford, PhD | Mar 25, 2024 | 4 min read
Influenza infection activates a pathway that leads to a detrimental drop in progesterone during pregnancy in mice.
A blue neuron extends into the distance with many protrusions.
Promoting Parenting Practices
Shelby Bradford, PhD | Feb 1, 2024 | 2 min read
Pregnancy hormones help mice prepare to take care of their young by altering activity in neurons.
The Epigenetic Origins of Allergy and Asthma
The Scientist Speaks Ep. 15 - The Epigenetic Origins of Allergy and Asthma
The Scientist | 1 min read
Epigenetic marks acquired from environmental exposures throughout life influence human health and may even transcend generations.
Infographic showing placenta development
Infographic: Early Placenta Development Sets the Stage
Danielle Gerhard, PhD | Dec 4, 2023 | 2 min read
During early pregnancy, the placenta remodels the uterine environment to support fetal growth
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
The Vaginal Microbiome is Finally Getting Recognized
Hannah Thomasy, PhD, Drug Discovery News | Sep 25, 2023 | 10+ min read
Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.
A fluorescence microscopy image of placenta tissue made up of cells dyed blue, purple, pink and green on a black background.
The Cellular Intricacies of the Human Placenta
Ida Emilie Steinmark, PhD | Jul 5, 2023 | 2 min read
Rare samples saved 35 years ago helped researchers map gene expression and cell differentiation in first trimester placentas.
Image of methylated DNA
Stress Increases Biological Age, But Recovery Can Revert It
Alejandra Manjarrez, PhD | Apr 21, 2023 | 2 min read
A new study relying on DNA methylation clocks suggests that the biological age of mouse and human cells can fluctuate in response to stressful events.
A mother mouse breastfeeds her offspring
Fast-Acting Nonhormonal Male Birth Control Prevents Pregnancy in Mice
Katherine Irving | Feb 15, 2023 | 5 min read
The “on demand” drug immobilizes sperm rather than limit their production, preventing 100 percent of pregnancies in an experiment.
Photo of Claudia Gerri
Claudia Gerri Studies the Mysteries of the Placenta
Katherine Irving | Feb 1, 2023 | 3 min read
At the Max Planck Institute of Molecular Cell Biology and Genetics, the developmental biologist is probing the maternal-fetal interface across mammalian species.
Illustration showing immunology during pregnancy
Infographic: How Immunology Can Influence Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 3 min read
Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.
Illustration of pregnancy and the immune system
Modulating Immunity to Improve Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 10+ min read
Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 
A portrait shot of Beryl Benacerraf, who wears a black shirt and gold necklace and smiles into the camera, on a bluish gray background.
Obstetrics “Giant” Beryl Benacerraf Dies at 73
Katherine Irving | Oct 26, 2022 | 2 min read
Benacerraf pioneered the use of ultrasound to diagnose fetal syndromes.
A black and white photo of a woman in a plumed hat in a laboratory classroom with several men
Birth of The Pill, 1956–1960
Andy Carstens | Oct 3, 2022 | 2 min read
Researchers overseeing the clinical trial for the first FDA-approved oral contraceptive claimed the drug gave the Puerto Rican participants power over their family planning. Critics claimed the women were exploited.
pregnant belly clad in hospital gown with IV line going into hand
Registry Review Casts Doubt on Causal Link Between Maternal Infection and Autism
Charles Q. Choi, Spectrum | Sep 26, 2022 | 4 min read
Maternal infection during pregnancy may be associated with autism, as previous studies have suggested—but perhaps not in a causal way.
Newborn baby rats lie in a basket
Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains
Bianca Nogrady | Sep 12, 2022 | 2 min read
Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.
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