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Image of the fly brain (grey) highlighting the population of neurons (pink) to which the gut-secreted peptide CCHa1 signals
A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study
The effect appears to be mediated by a gut-secreted peptide that signals to neurons in the brain that modulate the response to mechanical vibrations.
A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study
A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study

The effect appears to be mediated by a gut-secreted peptide that signals to neurons in the brain that modulate the response to mechanical vibrations.

The effect appears to be mediated by a gut-secreted peptide that signals to neurons in the brain that modulate the response to mechanical vibrations.

peptide

Bright purple and orange lactobacillus bacteria.
How a Specific Gut Bacterium May Trigger Type 1 Diabetes
Dan Robitzski | Aug 25, 2022 | 6 min read
What triggers type 1 diabetes has been difficult to prove, but a bacterium that produces an insulin-like peptide can give mice type 1 diabetes, and infection with the microbe seems to predict the onset of the disease in humans.
red ants coming out of dirt hole
Bull Ant Venom Evolved to Make Bites More Painful to Mammals
Dan Robitzski | Jul 5, 2022 | 2 min read
A peptide found in bull ant venom closely resembles a hormone of its primary predator, triggering hypersensitivity and making subsequent bites even more painful than the ones that came before.
The Ins and Outs of LC-MS
The Ins and Outs of LC-MS
Deanna MacNeil, PhD | 4 min read
From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.
An illustration depicting pores on a membrane
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
Sophie Fessl, PhD | Feb 14, 2022 | 3 min read
Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.
An APP-knockout neuron (right) shows extended axonal and reduced dendritic growth compared with a normal mouse neuron (left). Scale bar 50 µm.
Amyloid Precursor Protein Linked to Brain Development Mechanisms
Catherine Offord | Dec 1, 2021 | 2 min read
Researchers provide evidence that the Alzheimer’s-associated protein calibrates a signaling pathway that is conserved across the animal kingdom.
 Optimizing Protein Expression and Production
Technique Talk: Optimizing Protein Expression and Production
The Scientist | 1 min read
Learn how to efficiently produce large quantities of a biologically active protein.
RNA droplets
Image of the Day: Liquid Compartments
Nicoletta Lanese | Aug 28, 2019 | 1 min read
Membraneless organelles appear highly sensitive to ion concentrations in their environment.
Image of the Day: Ocean Wonder
Sukanya Charuchandra | Sep 4, 2018 | 1 min read
Molecules similar to those produced by sea anemones are neuroprotective in a mouse cell model of Alzheimer’s disease.
800x560-sept-15-2021
Using Nanopores to Sense and Sequence Proteins
The Scientist | 1 min read
Aleksei Aksimentiev and Stefan Howorka discuss challenges in amino acid sensing with nanopores and approaches to design efficient protein sequencing technology.
Nobel Prize–Winning Biologist Dies
Catherine Offord | Feb 19, 2018 | 2 min read
Günter Blobel, known for his work on the signal hypothesis of protein targeting, has died from cancer at age 81.
Molecule Similar to Peptides Detected in Protostars
Kerry Grens | Jun 9, 2017 | 2 min read
The dust surrounding emerging, Sun-like stars contains methyl isocyanate, an organic molecule.
Cancer Vaccines: Raising a T Cell Army
Niki Spahich, PhD | 1 min read
Vaccines against various forms of cancer prime the immune system to attack.
Amyloid Designed to Inactivate Cancer-Related Protein
Kerry Grens | Nov 13, 2016 | 1 min read
Researchers build a peptide that causes a receptor to form toxic, amyloid-like clumps in cells.
How to Track Translation in Living Cells
Ruth Williams | Oct 1, 2016 | 4 min read
Four independent research groups develop techniques for visualizing peptide production in living cells.
Scientists Catch Translation in the Act
Ruth Williams | Sep 30, 2016 | 1 min read
Newly developed techniques from four different groups rely on the same basic steps to track translation in live cells.
Tools for Drools
Kelly Rae Chi | Jul 1, 2015 | 8 min read
A general guide to collecting and processing saliva
A Multi-Cancer Diagnostic?
Kate Yandell | Jul 14, 2014 | 3 min read
Researchers report an ability to detect several types of cancer in blood samples based on signatures of immune response, but some are skeptical about the utility of such a test.
Centipede Venom Tops Morphine
Kerry Grens | Oct 1, 2013 | 2 min read
The substance targets the same ion channel that's mutated in people who don't feel pain.
Celebrated Neuroscientist Dies
Kate Yandell | Sep 23, 2013 | 2 min read
Candace Pert, who helped discover opioid receptors, has passed away at age 67.
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