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A Gut Feeling About Parkinson’s Disease
CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease.
A Gut Feeling About Parkinson’s Disease
A Gut Feeling About Parkinson’s Disease

CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease.

CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease.

Parkinson's disease

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
<em>The Scientist</em> poster&nbsp;
New Strategies for Repurposing Existing Therapies 
The Scientist | Aug 10, 2023 | 1 min read
Drug repurposing uses existing drugs beyond the scope in which they were originally approved by the Food and Drug Administration.
Bringing Gene Therapy to the Brain
Bringing Gene Therapy to the Brain
The Scientist Staff | 1 min read
In this webinar, Douglas Marchuk and Viviana Gradinaru will discuss how scientists can overcome physiological barriers preventing gene therapies from reaching the brain. 
3D rendered medical illustration of neurons containing Lewy bodies (small red spheres), accumulated proteins in brain cells that cause degeneration and are linked to Parkinson&rsquo;s disease.
The Bigger Protein Picture of Designing Parkinson’s Therapeutics
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers highlight protein structure considerations for designing inhibitors that target familial Parkinson’s disease mutations.
a mouse moves away from the camera, its left leg caught in a cloth
Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs
Katherine Irving | Feb 9, 2023 | 4 min read
Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.
Harnessing Metagenomics for Health and Disease Research
Harnessing Metagenomics for Health and Disease Research
The Scientist Staff | 1 min read
Discover how metagenomics approaches provide insights into human diseases.
Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Catherine Offord | Aug 1, 2022 | 5 min read
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
Amyloid plaques on axons of neurons
The Misunderstood Proteins of Neurodegeneration
Catherine Offord | Aug 1, 2022 | 10+ min read
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.
A woman with diabetes checks her blood glucose levels using a wearable biosensor patch on her upper arm, transmitting the results to a smartphone.
Wearable Biosensors and Their Applications
Rebecca Roberts, PhD | 5 min read
Allowing users to continually monitor biological signals over time, wearable biosensors pave the way toward personalized healthcare.
3D illustration showing neurons inside the brain
Experimental Pill to Treat Parkinson’s Is Safe, Trial Finds
Andy Carstens | Jun 10, 2022 | 2 min read
Testing in animals and lab-grown cells suggests the experimental drug could enhance the function of lysosomes within cells.
A pink and blue illustration of the central nervous system, visible through a translucent outline of a human head and shoulders, zooms in to show an illustration of interconnected neurons
Specific Brain Cells Linked to Parkinson’s Disease
Dan Robitzski | May 6, 2022 | 2 min read
Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.
TSS
Immune Cells and ALS: A Balance Between Life and Death
The Scientist | 1 min read
Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.
Photo of Ana Marija Jakšic
Ana Marija Jakšić Shapes Fruit Fly Brains
Chloe Tenn | Apr 18, 2022 | 3 min read
The Swiss Federal Institute of Technology Lausanne evolutionary neurobiologist is using Drosophila to investigate how organisms adapt to novel environments.
Bespectacled man wearing black shirt with arms folded looks at camera in front of lab cabinet
Neuropathologist John Trojanowski Dies at 75
Lisa Winter | Mar 18, 2022 | 2 min read
His work was pivotal to understanding the mechanisms of neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s.
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
The Scientist and PerkinElmer | 1 min read
Robin Ketteler and Hélène Plun-Favreau discuss the importance of autophagy and mitophagy regulation in neurodegenerative diseases.
Translucent, red-orange organs are shown inside a person’s transparent, blue torso. One region zooms in on blue lung alveoli covered by bright orange microbes.
Bacteria in the Lungs Can Regulate Autoimmunity in Rat Brains
Dan Robitzski | Mar 17, 2022 | 4 min read
Making specific alterations to the bacterial population in a rat’s lungs either better protects the animals against multiple sclerosis–like symptoms or makes them more vulnerable, a study finds—the first demonstration of a lung-brain axis.
Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022 | 4 min read
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist and Thermo Fisher Scientific | 1 min read
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021 | 3 min read
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
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