optogenetics

Sheena Josselyn discussed how she uses optogenetic tools to bias, express, and erase memories in mice.

Oxytocin released in a region of the hypothalamus helps mice remember who to avoid.

Scientists are a step closer to uncovering the neural changes that underlie sustained mental states.

Forgetting things appears to be a productive process and not a passive loss of information.

Brain tumors use the brain’s plasticity to promote their own growth.

In the developing zebrafish, a noisy and asynchronous activity jumpstarts the heart’s journey to coordinated beating.

Researchers find that an increased heart rate can induce anxiety in mice, given the right context.

A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.

Nine people with spinal injuries walked again after electrical stimulation, allowing researchers to pinpoint neurons likely underlying their recovery.

The Boston University neuroscientist wants to take the edge off traumatic memories by manipulating how they’re processed in the brain.

Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.

A study shows “sonogenetics” could be a useful new tool in neuroscience and other fields.

Signals from sweeteners and sugars are relayed from the gut to the brain by different neural pathways, a new study concludes.

Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.

Mice have neurons that connect to both eyes but only propagate the signal from one or the other, simplifying the information sent to the cerebral cortex.

This year’s winners are Dieter Oesterhelt, Peter Hegemann, Karl Deisseroth, Drew Weissman, Katalin Karikó, and David Baltimore.

Heated gold nanoparticles unleash the therapeutic activity of engineered CAR T cells.

Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions.