The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.
A growth factor found in the cerebrospinal fluid of young mice triggered the proliferation of myelin-making cells when injected into the brains of older mice.
Angie Voyles Askham, Spectrum | Feb 17, 2022 | 4 min read
A study shows that a molecule produced by intestinal microbes can enter the brain and that its presence is also associated with altered brain connectivity.
A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.
A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.
Ben Barres recast glial cells from supporting actors to star performers, crucial for synaptic plasticity in the brain and for preventing neurodegenerative disorders.
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.