next generation sequencing

Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.

Gang Fang’s new metagenomics method helps sequence rare bacteria.

Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Researchers created a model that uses clinical testing data to locate the primary site of cancer cells with no known origin, likely improving survival.

Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types. 

Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

Researchers show how a toxic therapy helped identify a mummy using preserved DNA.

Researchers identify what makes certain people more likely to contract leprosy than others.

Researchers use genetic clues to track the spread of antibiotic resistant bacteria from the environment to patients.

Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness.

Analyses of more than 300 ancient human genomes show that Hepatitis B virus has infected humans for at least 4,500 years and has much older origins than modern viral genomes would suggest.

Ambry Genetics CEO Aaron Elliott discusses his team’s recent analysis of 20,000 clinical next-generation sequencing panels.