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An artist’s representation of the human respiratory system with pink airways on a blue and black background.
A Gene Editing System Corrects Cystic Fibrosis Mutation
An optimized version of prime editing technology raises the possibility of a one-time treatment for cystic fibrosis.
A Gene Editing System Corrects Cystic Fibrosis Mutation
A Gene Editing System Corrects Cystic Fibrosis Mutation

An optimized version of prime editing technology raises the possibility of a one-time treatment for cystic fibrosis.

An optimized version of prime editing technology raises the possibility of a one-time treatment for cystic fibrosis.

News

A syringe inserted into a vial of vaccine.
Engineered Yeast Brew a Vaccine Adjuvant 
Sahana Sitaraman, PhD | Sep 3, 2024 | 3 min read
Ever since its discovery in the 1900s, the production of a potent vaccine adjuvant relied on the Chilean soapbark tree. Now, yeast can make the molecule.
Cartoon of a young girl sitting at a table looking at a collection of cartoon viruses.
Crafting Science Stories for Young Audiences
Danielle Gerhard, PhD | Sep 2, 2024 | 7 min read
Finding a narrative that resonates with the audience and serving it in their preferred format helps make science engaging, relatable, and fun.
3D illustration of a DNA molecule with sparkling effects symbolizing.
A Prime-Editing Based Approach Records Cellular Genetic History
Maggie Chen | Aug 30, 2024 | 3 min read
Researchers developed a technique, ENGRAM, to keep a running log of the elements that control gene expression in cells. 
A micrograph shows grey sickle-shaped nanovials containing single, fluorescent green mesenchymal stem cells. Some of the cells have secreted high levels of magenta-colored extracellular vesicles.
Tiny Test Tubes Sort Stem Cells for Improved Therapy
Rebecca Roberts, PhD | Aug 29, 2024 | 4 min read
Mesenchymal stem cells with high levels of extracellular vesicle secretion promote vascular regeneration and improve heart function in mice.
On the left is a brain in blue connect by blue electricity-like lines to a heart in red on the right side of the image.
Can the Brain Help Heal a Broken Heart?
Hannah Thomasy, PhD | Aug 28, 2024 | 6 min read
Stimulation of neural reward pathways may help mice recover from heart attacks.
A small blue cell undergoing cell death next to a larger amber cell with extensive projections.
Older Oligodendrocytes Live Longer Despite Damage
Nicholas Miliaras, PhD | Aug 28, 2024 | 3 min read
Tracking oligodendrocytes across their lifespans could help scientists better understand neuronal aging and degenerative diseases. 
Photograph of the end of a tattoo gun and pots of different colored ink on a napkin.
FDA Found Anaerobic Bacteria in Sealed Tattoo Inks
Shelby Bradford, PhD | Aug 27, 2024 | 3 min read
The presence of microbes in tattoo inks raises concerns regarding the products’ safety.  
Pseudo-colored scanning electron microscope image of the algae microrobot with the algae in green and the drug-filled nanoparticles in orange.
Green Warriors: Algae Microrobots Set to Combat Metastasis
Laura Tran, PhD | Aug 26, 2024 | 4 min read
Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.
Image of a Baobab tree with star trails overhead.
Night Science Podcast: A Walk on Science’s Creative Side
Laura Tran, PhD | Aug 23, 2024 | 5 min read
Researchers Itai Yanai and Martin Lercher host a unique podcast where they explore the creative process of generating ideas for scientific research.
Six tubes, each with black dots representing flies, each fly encircled in blue, green, or red.
Combating Age-Related Motor Decline
Aparna Nathan, PhD | Aug 23, 2024 | 4 min read
Increasing levels of the protein Trio preserved synaptic function and motor abilities in aging flies.
In the foreground, a magnifying glass hovers over a strand of DNA, revealing information hidden in the sequence. Binary code and silhouettes of people are in the background. 
Biotechs Bolster Biosecurity to Safeguard the Future of Nucleic Acid Sequencing
Danielle Gerhard, PhD | Aug 22, 2024 | 10 min read
Synthetic DNA can pose significant biosecurity risks. Experts call for more screening by providers and institutions to mitigate security concerns.
A small red protein structure of the WW domain surrounded by a tubular wave of water.
From Symphony to Structure: Listening to Proteins Fold
Rohini Subrahmanyam, PhD | Aug 21, 2024 | 4 min read
By assigning sounds to the dynamic bonds within proteins, scientists gathered new insights on protein folding.
3D rendering of a transparent human torso to show the lungs and bronchiole structures in them.
Prenatal Inflammation Makes Mice Susceptible to Asthma
Shelby Bradford, PhD | Aug 20, 2024 | 4 min read
Maternal immune responses during mice gestation led to a hyperactive population of innate-like immune cells in offspring that contributed to altered lung composition and function.
A woman and a child sitting on a couch blowing their noses. 
A Better Mucus Model
Aparna Nathan, PhD | Aug 20, 2024 | 4 min read
A more realistic model of the mucus layer that lines the lungs and gut could provide important insights into the function of this critical defensive barrier.
Image of a woolly mammoth skin from the Siberian permafrost.
Rebuilding the Genome of Woolly Mammoths
Laura Tran, PhD | Aug 19, 2024 | 4 min read
A well-preserved 52,000-year-old woolly mammoth skin sample with fossils of ancient chromosomes could offer a glimpse into the history of life.
A circular pattern of red, blue, and yellow bolts of electricity on a black background.
Current Events: Bioelectrical Gradients Guide Stem Cell Morphology
Iris Kulbatski, PhD | Aug 16, 2024 | 3 min read
Electrically conductive hydrogels may hold the power to advance the use of stem cells for neural engineering. 
An illustration of lungs being infected by microbes.
Bacteria Put on an Invisibility Cloak to Cause Asymptomatic Infections 
Sahana Sitaraman, PhD | Aug 15, 2024 | 5 min read
Biofilms prevent Pseudomonas aeruginosa toxins from being detected by sensory neurons, tricking the body into not looking sick.
Image shows the mosquito Aedes aegypti on top of human skin.
A Mosquito Protein Facilitates Zika Infection
Claudia Lopez-Lloreda, PhD | Aug 14, 2024 | 3 min read
A salivary protein in mosquitos can suppress host immune activity and aid viral transmission.
Cartoon image of floating transparent spheres with smaller blue spheres inside them.
Study Reveals a Cell-Eat-Cell World
Aparna Nathan, PhD | Aug 13, 2024 | 3 min read
From normal vertebrate development to tumor cell cannibalism, cell-in-cell events occur in many different contexts across the tree of life
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