News & Opinion

Human cells repair RNA breaks induced by a programmable CRISPR system, paving the way for temporary treatments for genetic diseases.

During pregnancy, fetal cells invade maternal tissues and can persist for decades, but the effects of these non-self cells remain largely obscure.

Researchers mapped tissue remodeling during colitis development in mice to explore how diverse cell types contribute and respond to the disease.  

Carola Vinuesa’s research has illuminated the genetics of lupus and helped to exonerate a mother falsely accused of murdering her four children. 

Epigenetic control of gene expression can switch on genes that push cell division into overdrive independently of genetic faults.

A new microfluidics cell culture model recapitulates the basic biology of gut touch.

A lower-resolution spatial epigenomics method offers a cost-effective alternative to traditional single-cell approaches.

A tickborne virus uses cholesterol receptors to worm its way into the cell.

An essential nutrient and the gut flora, thought to have separate but important roles in the immune response, join forces.

Reactive oxygen species cause mutations to DNA bases that can lead to cancer, but the long-blamed mitochondria could have been wrongfully charged.

Removing microRNA that caused conversion of male mice embryos into female sheds light on key noncoding elements in sex determination.

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

In plants, sugar transport and microbial community composition go hand in hand. 

A new system for simultaneous genomic edits could unlock better models of complex diseases.

Magdalena Zernicka-Goetz followed the aesthetic allure of the embryo to better understand the start of development.

A brain rhythm in the hippocampus tags events for replaying during sleep, revealing a potential mechanism for selecting experiences for long-term storage. 

Researchers explore how video games can improve scientific understanding of the tree of life.

Biobanks fuel the multiomics-based practice of personalized oncomedicine and cancer biomarker discovery.

By tinkering with branched mRNA structures, scientists lay the groundwork to build better vaccines in the future.