Psychedelics are evolutionarily ancient compounds produced by fungi, plants, and microbes. Humans also synthesize psychedelics. Researchers want to know how and why.
A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome.
The Duke University cell biologist uses live-cell microscopy to reveal how brain cells rid themselves of damaged mitochondria and what goes wrong in neurodegenerative disease.
Performing complex cognitive tasks leads to glutamate accumulating in a key region of the brain, a study finds, which could explain why mental labor is so exhausting.
Synapses in the mouse neocortex can release multiple packages of neurotransmitters, suggesting that connection strength is more flexible than previously thought.
In a first-of-its-kind study, researchers monitored subsecond changes in levels of the neurotransmitters in the human brain, unlocking new insight into their function.
The biochemical mechanisms in the brain underlying suicidal behavior are beginning to come to light, and researchers hope they could one day lead to better treatment and prevention strategies.