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mRNA vaccine

Rebecca Roberts, PhD | Nov 30, 2023 | 3 min read

By targeting resident memory T cells in the liver, a novel mRNA malaria vaccine prevented infection, even in those with prior exposure.

A vial labeled “mRNA vaccine” and a syringe on a blue background.

An Updated Approach to mRNA Vaccine Quality Assessment

Deanna MacNeil, PhD | Nov 13, 2023 | 3 min read

Researchers developed and validated a sequencing method for mRNA vaccines, moving the manufacturing field forward by linking established technologies with translational applications.

<em >The Scientist</em>’s Journal Club: Infectious Diseases

The Scientist’s Journal Club: Infectious Diseases

The Scientist | 1 min read

Scientists present the latest research on infection prevention and treatment, including COVID-19 and tropical infectious diseases.

A triangular sign affixed to a tree displaying the silhouette of a tick.

Newly Developed mRNA Vaccine Protects Against Lyme Disease

Charlene Lancaster, PhD | Nov 13, 2023 | 5 min read

Leveraging the same mRNA platform used for COVID-19 vaccines, researchers generated a vaccine that prevents mice from acquiring Lyme disease.

Black and gold sketch of Katalin Karikó and Drew Weissman.

Nobel Prize for mRNA Vaccines

Danielle Gerhard, PhD | Oct 2, 2023 | 5 min read

Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.

Building Bridges for Translational Research - A Special Podcast Series

The Scientist and Cytiva | 2 min read

Translational scientists discuss their experiences taking preclinical concepts to the market.

SARS-CoV-2 self-assembling virus-like nanoparticle with spike proteins protruding from the surface.

New Technology Improves SARS-CoV-2 mRNA Vaccine-Induced Immune Responses

Elina Kadriu | May 30, 2023 | 3 min read

mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants.

RSV Vaccines That Work?

Rachael Moeller Gorman | Feb 16, 2023 | 10+ min read

Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.

3d render illustration of Single strand ribonucleic acid.

Message in a Bottle: Developing mRNA Therapeutics

The Scientist and Mirus Bio | 3 min read

A high efficiency, low toxicity method for direct RNA delivery into cells.

Four glass vials sit on a reflective tabletop next to a syringe. Each is labeled as a subsequent dose in a four-dose series of COVID-19 vaccines.

What We Know About Getting a Second Booster Shot of COVID-19 Vaccines

Dan Robitzski | Aug 11, 2022 | 10+ min read

Studies show that a fourth mRNA vaccine dose offers the elderly and other high-risk groups strong protection against hospitalization and death from COVID-19, but experts say benefits for other populations may be more limited.

Brick building with tall windows and white letters out front that say "Food and Drug Administration"

FDA Limits Use of J&J Vaccine, Citing Safety Concerns

Natalia Mesa, PhD | May 6, 2022 | 2 min read

US adults are now only eligible for the vaccine under certain circumstances.

A masked doctor in a white coat and blue gloves administers a vaccine into the arm of a masked child.

Pfizer Vaccine Less Protective for Younger Kids: Preprint

Dan Robitzski | Feb 28, 2022 | 3 min read

The vaccine’s effectiveness in children ages 5 to 11 rapidly declined over the course of a month, according to new research that looked at the health outcomes of hundreds of thousands of children in New York during the Omicron surge.

Stethoscope on top of form and clipboard

Robert Malone Targets Physician Who Alerted Medical Board to Misinformation

Catherine Offord | Feb 19, 2022 | 8 min read

A Hawaii hospital worker who reported the controversial scientist to the Maryland Board of Physicians was subjected to harassment and a retaliatory complaint after Malone made his name and location public.

People waiting in line for COVID Vaccine

CDC: COVID-19 Booster Effectiveness Wanes After Four Months

Natalia Mesa, PhD | Feb 14, 2022 | 2 min read

The agency also finds that third shots prevented hospitalizations during the Omicron wave.

CAR T Cells Mend Broken Mouse Hearts

Sophie Fessl, PhD | Jan 6, 2022 | 4 min read

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.

Antibodies in breastmilk from SARS-CoV-2 infection or mRNA vaccination neutralize the virus.

Antibodies Against SARS-CoV-2 in Breast Milk Differ Between Vaccinated and Infected Mothers

Roni Dengler, PhD | Dec 6, 2021 | 3 min read

All antibodies against SARS-CoV-2 found in breast milk neutralized the virus.

black-legged deer tick waits on leaf for host to feed on

A Lab-Stage mRNA Vaccine Targeting Ticks May Offer Protection Against Lyme and Other Tick-Borne Diseases

Andaleeb Sajid | Nov 18, 2021 | 3 min read

NIH researcher Andaleeb Sajid discusses her study’s finding that ticks were unable to feed on vaccinated guinea pigs, preventing transmission of the pathogen that causes Lyme disease.