The Resilience of Monoclonal Antibodies and their Makers
The Resilience of Monoclonal Antibodies and their Makers
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
monoclonal antibodies
Infographic: Phage Display Allows Rapid Screening of Millions of Peptides
Shelby Bradford, PhD | Dec 4, 2023 | 3 min read
A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Boosting the Efficiency of Therapeutic Antibody Development
The Scientist Staff | 1 min read
In this webinar, Daryl Cole will highlight how new technologies improve antibody discovery and production.
Mean, Green, Antibody-producing Machines
Shelby Bradford, PhD | Dec 1, 2023 | 2 min read
A plant-based monoclonal antibody goes head-to-head with its commercial counterpart to target tumors in mice.
Multiple Targets, Infinite Possibilities
The Scientist Staff | Aug 1, 2023 | 2 min read
Multispecific antibodies are rising stars in the field of antibody therapeutics, offering better specificity, targeting ability, and therapeutic effects than traditional monoclonal antibodies.
Teaching Old Drugs New Tricks
The Scientist Staff | 1 min read
Learn how scientists develop antibody drug conjugates as therapies for age-related diseases.
Opioid Vaccines as a Tool to Stem Overdose Deaths
Tori Rodriguez | Jun 13, 2022 | 10+ min read
Researchers are turning to the immune system for help in treating addiction and preventing overdose.
Ebola Lurking in Brain Fluid Kills Monkeys Weeks After Recovery
Dan Robitzski | Feb 9, 2022 | 4 min read
New research reveals where the virus was hiding and hints at how to truly purge it from the body.
Building Broader B Cell Diversity for Better Monoclonal Antibody Discovery
The Scientist Staff | 1 min read
In this webinar, Vincent Pai will discuss how the latest automated single B cell functional screening technology helps researchers meet the demands for new monoclonal antibody candidates.
Antiviral Pill Lowers Risks of COVID-19 Hospitalization, Death
Chloe Tenn | Oct 1, 2021 | 3 min read
Merck reports that its antiviral molnupiravir was effective against early stages of COVID-19 in high-risk patients in a Phase 3 clinical trial.
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
Kerry Grens | Jun 7, 2021 | 2 min read
A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.
Accelerating Antibody Discovery for Difficult Targets
The Scientist | 1 min read
François Romagné will discuss how RNA immunization and single cell screening enhance antibody generation for poorly immunogenic proteins.
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Amanda Heidt | May 4, 2021 | 5 min read
A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.
Regeneron Cocktail Stumbles Against SARS-CoV-2 Variant in Vitro
Marcus A. Banks | Mar 1, 2021 | 3 min read
A treatment of two monoclonal antibodies against SARS-CoV-2 is ninefold less effective in the lab against the B.1.351 variant than against the dominant version of the virus.
The Basics of the Tumor Microenvironment
Johanna Pruller, PhD | 4 min read
Learn about the tumor microenvironment (TME), a key influencer of cancer growth, spread, and treatment success.
Eli Lilly Halts Antibody Trial in Hospitalized COVID-19 Patients
Ashley Yeager | Oct 27, 2020 | 1 min read
Recent data show that the drug bamlanivimab, also known as LY-CoV555, does not appear to help those with severe cases of COVID-19, but trials continue for milder cases.
Antibody-Based Drug May Reduce COVID-19 Hospitalizations: Study
Lisa Winter | Sep 17, 2020 | 2 min read
Eli Lilly reports a 72 percent reduction in hospitalization risk among patients who received its monoclonal antibody compared to those who received a placebo.
Understanding Hybridoma Technology for Monoclonal Antibody Production
Alpana Mohta, MD | 5 min read
By fusing antibody-producing cells with immortal myeloma cells, researchers produce reliable supplies of highly specific antibodies.
Bacterial Superglue Enables Antiviral Antibody Discovery
Ruth Williams | Jul 13, 2020 | 3 min read
Testing out combinations of antiviral proteins from llamas could help researchers create potent virus-neutralizing multimers.