microRNA

Removing microRNA that caused conversion of male mice embryos into female sheds light on key noncoding elements in sex determination.

During her routine tasks in the laboratory, Mallory Havens suddenly found herself navigating a toxic terrain. 

When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.

Upregulation of a specific microRNA in the brain lessened anxiety and reduced the expression of stress-related genes in mice. 

The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought.

Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.

Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.

Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

Neurologically important noncoding RNAs come in many shapes and sizes.

The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.

From his student days in veterinary medicine in Ethiopia to running a lab on metastasis at MD Anderson Cancer Center, Debeb has a passion for understanding how living things work.

A noninvasive saliva test accurately identified concussions in a study of hundreds of rugby players.

A finding of distinct patterns of gene-regulating RNA snippets in the blood of ME/CFS patients in response to a stress test could pave the way for a diagnostic tool for the condition and help untangle its underlying mechanisms.

Weill Cornell Medicine geneticist Christopher Mason speaks with The Scientist about a bolus of new work on the physiological, cellular, and molecular effects of leaving Earth.

Collagen inside ankles has more turnover than that in hips, thanks to the action of microRNAs.

Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.