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MRI scan of a human head in profile
Gut Microbe Metabolites Lower Levels of Toxic Tau
Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.
Gut Microbe Metabolites Lower Levels of Toxic Tau
Gut Microbe Metabolites Lower Levels of Toxic Tau

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

metabolites

Photo of a line of grassy plants with the roots under the soil visible.
Plants Defend Themselves Against Heavy Metals
Shelby Bradford, PhD | Jun 13, 2024 | 3 min read
A metabolite from maize roots protects the plants against arsenic toxicity.
Abstract drawing of microbes.
Exploring Microbial Dark Matter
Kamal Nahas, PhD | Apr 19, 2024 | 4 min read
An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 
A block of cheddar cheese pictured here with various accompaniments. 
Cheddar Cheese Lovers Have Interactive Microbes to Thank
Vaishnavi Sridhar, PhD | 3 min read
Scientists used a commercial year-long cheddar making process to show how various bacterial communities interact and contribute to the distinct flavor of cheddar.
Fatty Feasts May Come at an Immune Cost
Shelby Bradford, PhD | Jan 25, 2024 | 4 min read
Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.
Cheese wheels with moldy rinds on a wooden plank
Deleting a Gene Quells a Pesky Cheese-Destroying Fungus
Natalia Mesa, PhD | Jun 30, 2023 | 3 min read
Fungi disrupt microbial communities on cheese by making antibiotics. 
Droplet of DNA lysate
Optimizing Sample Homogenization
The Scientist and Bertin Technologies | 3 min read
Discover how the latest homogenization technology improves and simplifies the processing of any biological sample.
a mouse moves away from the camera, its left leg caught in a cloth
Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs
Katherine Irving | Feb 9, 2023 | 4 min read
Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.
Pink neutrophils on a white background.
Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment
Alejandra Manjarrez, PhD | Jan 5, 2023 | 3 min read
The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.
Measuring Metabolites to Prevent, Diagnose, and Treat Cancer
Niki Spahich, PhD | 1 min read
Metabolomics research highlights molecules important for cancer prevention, diagnosis, and treatment.
Group of cells stained in either blue or green in a black background.
Diabetes Marker Linked to COVID-19 Severity in Mice
Alejandra Manjarrez, PhD | May 16, 2022 | 3 min read
A sugar that’s less abundant in the blood of people with diabetes binds to SARS-CoV-2’s spike protein and disrupts the virus’s ability to fuse with cells.  
Dogs under blanket together stock photo
A Nose by Any Other Name: Tracking the Scent of Tumor Metabolic Waste
Iris Kulbatski, PhD | Apr 11, 2022 | 3 min read
The unique odor profiles of tumors can be used to develop diagnostic sensing tools.
The Community-Wide Effort to Standardize QA/QC for Metabolomics and Lipidomics
The Scientist | 1 min read
Perspectives on the basics and future of QA/QC
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan, PhD | Apr 8, 2022 | 5 min read
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
white mouse running on a light blue wheel
Tinkering with Gut Microbes Boosts Brain Plasticity in Mice
Sophie Fessl, PhD | Jan 13, 2022 | 4 min read
Intestinal bacteria contribute to the effect of stimulating environments on the brain’s ability to adapt, a study concludes.
Performing Metabolomic and Functional Proteomic Analyses on a Heterogenous Cancer Cell Population
The Scientist Creative Services Team in Collaboration with IsoPlexis | 2 min read
A tumor metabolome panel identifies altered cell states that lead to drug tolerance.
major depressive disorder depression microbiome bacteria virus phage bacteriophage metabolite metabolomics
Distinct Microbiome and Metabolites Linked with Depression
Rachael Moeller Gorman | Dec 9, 2020 | 4 min read
The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.
Nutrition Researchers Can Determine What You’ve Been Eating
Amber Dance | Dec 1, 2020 | 10+ min read
The study of diet, long plagued by inaccuracies in self reports, is entering a new age of precision with the methods of metabolomics.
Infographic: Deciphering Diet from Blood and Urine Samples
Amber Dance | Dec 1, 2020 | 1 min read
Nutrition researchers are beginning to use metabolomics to determine how healthy subjects’ diets are, and even to reveal specific properties of the foods they eat.
firefighters emergency responders 9/11 world trade center terrorist attacks september 11, 2001 obstructive airway disease pulmonary function lung health metabolites diet omega-3 fatty acids
Metabolites May Predict Lung Injury in 9/11 First Responders
Emma Yasinski | Sep 3, 2019 | 3 min read
Firefighters who didn’t develop obstructive airway disease after the World Trade Center attacks had higher levels of omega-3 fatty acids and other factors that hint at possible protective effects of diet.
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