metabolism
Exploring Microbial Dark Matter
Kamal Nahas, PhD | Apr 19, 2024 | 4 min read
An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds.
Lose the Fat and Curb Parasitic Infection
Mariella Bodemeier Loayza Careaga, PhD | Mar 1, 2024 | 2 min read
Trypanosoma brucei infection induces fat breakdown, but this strategy benefits the host.
An Introduction to Metabolomics
Rebecca Roberts, PhD | 5 min read
As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.
Why Don’t Hummingbirds Get Diabetes?
Hannah Thomasy, PhD | Feb 1, 2024 | 2 min read
Astronomically high blood sugar is no problem for these tiny speed demons.
A Snapshot of How Obesity Transforms Fat
Aparna Nathan, PhD | Oct 5, 2023 | 3 min read
Spatial methods reveal immune cell formations in fat during early obesity.
Emergent Recombinant Proteins in Clinical Diagnostics
Scripps Laboratories | 1 min read
A new era of reliable recombinant proteins makes it possible for researchers to replace tissue-derived biomarkers in a variety of diagnostic assays.
Circadian Signaling Affects T Cell Responses to Vaccination
Nathan Ni, PhD | Aug 9, 2023 | 3 min read
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
An Exercise-induced Liver Enzyme Boosts Metabolism
Natalia Mesa, PhD | Jul 7, 2023 | 3 min read
Exercise drives the liver to produce the CES2 enzyme, which circulates in blood and delivers some of the benefits of exercise in mice.
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
Yeast Cells Reconfigure Their Metabolomes to Live Longer
Danielle Gerhard, PhD | Jul 5, 2023 | 2 min read
Yeast cells share metabolites through extracellular space to extend the lifespan of the entire community.
Gut Bacteria Contribute to Anorexia
Kamal Nahas, PhD | May 1, 2023 | 3 min read
Microbiomes transplanted from women with anorexia nervosa into mice enhanced symptoms of the eating disorder, such as rapid weight loss and reduced appetite.
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
The Scientist and PerkinElmer | 1 min read
Robin Ketteler and Hélène Plun-Favreau discuss the importance of autophagy and mitophagy regulation in neurodegenerative diseases.
Rare Autism-Linked Mutation Starves Growing Neurons of Essential Nutrients
Lauren Schenkman, Spectrum | Apr 18, 2023 | 4 min read
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
The Scientist Speaks - Virulence Meets Metabolism: The Unique Evolution of Staphylococcus aureus
Niki Spahich, PhD | 1 min read
Anthony Richardson discusses what makes Staph especially dangerous for people with diabetes.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
The Smell of Food Affects Metabolism in Fasting Mice
Shafaq Zia | Nov 18, 2022 | 3 min read
The odor prompted the animals’ fat cells to release lipids into circulation.
Examining Altered Glycobiology in Cancer
The Scientist and Vector Laboratories | 1 min read
Changes to protein glycosylation play a major role in dictating cancer progression and prognosis, but could they also present biomarkers or therapeutic targets?
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
Alejandra Manjarrez, PhD | Nov 1, 2022 | 3 min read
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.