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An image of neurons, astrocytes, and other glial cells acquired using fluorescence microscopy.
Troubleshooting Fluorescence Microscopy Experiments
Delve into the tactics used by scientists to overcome fluorescence microscopy’s greatest obstacles.
Troubleshooting Fluorescence Microscopy Experiments
Troubleshooting Fluorescence Microscopy Experiments

Delve into the tactics used by scientists to overcome fluorescence microscopy’s greatest obstacles.

Delve into the tactics used by scientists to overcome fluorescence microscopy’s greatest obstacles.

Live-cell imaging

An illustration of a dividing cancer cell.
Striking a Balance for Perfect Images
The Scientist Staff | Oct 2, 2023 | 2 min read
Advanced microscope systems enable researchers to perform high-resolution live-cell imaging, while maintaining cellular health.
CAR T Cells Derived from Stem Cells Target HIV Tissue Reservoirs in Monkeys
Berly McCoy, PhD | May 25, 2021 | 3 min read
Transplanted CAR stem cells persisted long term and showed multilineage engraftment in tissues that harbor HIV.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Engineered Immune Cells Eliminate Brain Cancer in Mice
Brooke Dulka, PhD | May 25, 2021 | 2 min read
Researchers developed a new CAR T-cell therapy that targets specific growth factor receptors in glioblastoma to eliminate brain tumors.
Environmental Cues Keep CAR T Cells on Track
Aparna Nathan, PhD | May 25, 2021 | 4 min read
Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.
Visualizing apoptosis in a DU-145 cancer cell
Observing Cells in Their Natural State with Digital Holographic Cytometry
The Scientist and Phase Holographic Imaging | 3 min read
Technological and engineering advances let researchers delve deeper into cell function and behavior in physiological and pathological settings.
2019 Top 10 Innovations
The Scientist | Dec 1, 2019 | 10+ min read
From a mass photometer to improved breath biopsy probes, these new products are poised for scientific success.
Microscopy and Imaging Leader Shinya Inoué Dies
Jef Akst | Oct 7, 2019 | 1 min read
The long-time Marine Biological Laboratory scientist was known for using his own hand-built microscopes to image the dynamics of live cells.
Fluorescence microscopy image of cells expressing fluorescent biosensors. Green and magenta fluorescence is observed outside of the cell nuclei.
Choosing Fluorescent Reagents for Every Live Cell Application
The Scientist and MilliporeSigma | 4 min read
Scientists gain unique insights into active biological processes with specific fluorescent probes, dyes, and biosensors.
Image of the Day: Bad Behavior
Kerry Grens | Dec 12, 2018 | 1 min read
A deep learning program can identify cells with higher metastatic potential based on the way they look and move.
Image of the Day: Bundle of Nerves
Sukanya Charuchandra | Jul 26, 2018 | 1 min read
Live-cell imaging reveals the secrets of innervation in the pancreas of zebrafish.
Whole-Well Brightfield Cell Counting with the Latest in Microplate Imaging Technology 
Whole-Well Brightfield Cell Counting with the Latest in Microplate Imaging Technology
The Scientist | 1 min read
In this webinar, Magdalena Eckschlager and Christopher Wolff will discuss how cutting-edge neural network-based algorithm technology enables label-free, live cell imaging and analysis.
Image of the Day: Lit Up
Sukanya Charuchandra | Jul 24, 2018 | 1 min read
Researchers have updated a method to look at biochemical activities inside living cells.
Image of the Day: Eye-Opener
Sukanya Charuchandra | Jul 17, 2018 | 1 min read
An open-source microscopy method can super-resolve live cells even under low lighting.
800x560-oct-5-2021
Technique Talk: Live-Cell Imaging Strategies to Quantify Phagocytosis
The Scientist Creative Services Team in collaboration with Sartorius | 1 min read
Discover how to image and quantitate phagocytosis in real time
Watching Live Cells
Jef Akst | Aug 28, 2015 | 2 min read
An international team brings the new technology of super-resolution imaging to the world of the living.
Lights, Camera, Action
Jessica Wright | Jan 1, 2014 | 9 min read
A guide for doing in vivo microscopy on neurons in the mammalian brain
Whole-Slide Imaging and Beyond: A New Open Platform for Scanning and Bioimaging
The Scientist | 1 min read
In this webinar brought to you by MMI, learn how scientists use CellScan for a variety of lab applications, such as routine photo-documentation, whole-slide scanning, fluorescence imaging, time-resolved live-cell imaging, and combinations of these techniques.
A Room with a View
Amber Dance | Feb 1, 2013 | 8 min read
Live-cell imaging forces cells to perform in an unnatural environment, but with the right chamber, you can keep them warm and comfortable.
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