liquid chromatography
Advancing Oligonucleotide Characterization for Quality Control
Shimadzu | Aug 6, 2024 | 1 min read
Liquid chromatography-mass spectrometry allows scientists to accurately assess the quantity and quality of synthesized oligonucleotides.
![Image of The 84-Gun Danish Warship "Dronning Marie" in the Sound by Christoffer Wilhelm Eckersberg, a painting that depicts one large and two small Danish ships in the sea.](https://cdn.the-scientist.com/assets/articleNo/71966/aImg/53442/boat-800x560-t.jpg "Image of The 84-Gun Danish Warship "Dronning Marie" in the Sound by Christoffer Wilhelm Eckersberg, a painting that depicts one large and two small Danish ships in the sea.")
Uncovering Secrets of Historic Paintings in the Modern Laboratory
Niki Spahich, PhD | Jun 26, 2024 | 6 min read
Heritage scientist Fabiana Di Gianvincenzo uses proteomics to identify protein damage and unusual materials in historic paintings and textiles.
The Perils of a High-Pressure Experiment
Danielle Gerhard, PhD | Jun 3, 2024 | 2 min read
When Carl Hanson accidentally reinvented high-performance liquid chromatography, he landed in the hospital.
An Introduction to Metabolomics
Rebecca Roberts, PhD | Oct 17, 2023 | 5 min read
As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.
The Latest Strategies for Manual and Automated Protein Purification
Cytiva | Sep 15, 2023 | 1 min read
With the right guidance, researchers can select the appropriate protein purification workflow to meet their unique needs.
The Ins and Outs of LC-MS
Deanna MacNeil, PhD | Jul 24, 2023 | 4 min read
From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.
Technique Talk: The Fundamentals of Mass Spectrometry-Based Proteomics
The Scientist | May 23, 2023 | 1 min read
Learn the basics of proteomics analysis and nanoLC-MS/MS data acquisition.
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | Nov 4, 2022 | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Bull Ant Venom Evolved to Make Bites More Painful to Mammals
Dan Robitzski | Jul 5, 2022 | 2 min read
A peptide found in bull ant venom closely resembles a hormone of its primary predator, triggering hypersensitivity and making subsequent bites even more painful than the ones that came before.
Matching Water Purity to Fit Experimental Needs
ELGA Veolia | Sep 24, 2021 | 1 min read
Do not overlook water purity as a determinant of experimental outcome.
Pure and Simple: Water Quality Determines Experimental Sensitivity
ELGA Veolia | Jul 29, 2021 | 1 min read
Reliably detect trace amounts of chemicals in complex samples.
Measuring Metabolites to Prevent, Diagnose, and Treat Cancer
Niki Spahich, PhD | Jun 11, 2021 | 1 min read
Metabolomics research highlights molecules important for cancer prevention, diagnosis, and treatment.
The Community-Wide Effort to Standardize QA/QC for Metabolomics and Lipidomics
The Scientist | Apr 27, 2021 | 1 min read
Perspectives on the basics and future of QA/QC
Lipid Expert and Babraham Institute Director Michael Wakelam Dies
Amy Schleunes | Apr 7, 2020 | 2 min read
Wakelam, who died of a suspected COVID-19 infection, is remembered for his research on the physiological function of lipids.
Metabolomics Data Under Scrutiny
Ashley P. Taylor | Sep 15, 2017 | 4 min read
Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.
Resolving Separation Anxiety
Nicholette Zeliadt | Jun 1, 2013 | 9 min read
Continuing innovations in liquid chromatography column technology are improving the speed and separation efficiency of HPLC.