LC-MS

An illustration of an antisense oligonucleotide bound to an mRNA molecule.

Advancing Oligonucleotide Characterization for Quality Control

Shimadzu | Aug 6, 2024 | 1 min read

Liquid chromatography-mass spectrometry allows scientists to accurately assess the quantity and quality of synthesized oligonucleotides.

The Ins and Outs of LC-MS

Deanna MacNeil, PhD | Jul 24, 2023 | 4 min read

From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.

a mouse moves away from the camera, its left leg caught in a cloth

Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs

Katherine Irving | Feb 9, 2023 | 4 min read

Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.

Enable Effective Drug Development with Improved Multiomics

Multiomics: Avoid Getting Lost in Translation

SCIEX | Jan 26, 2023 | 1 min read

Translational research and drug discovery meet at the intersection of novel multiomics technologies.

Learn how to optimally detect contaminants in complex samples

Detecting Contaminants in Complex Drug Samples

SCIEX | Jan 25, 2023 | 1 min read

By optimizing chromatography and mass spectrometry methods, scientists overcome challenges in identifying contaminants such as N-nitrosamines.

Reduce background noise in chromatography with fresh ultrapure water

Increasing Chromatography Sensitivity with Ultrapure Water

Sartorius | Dec 29, 2021 | 1 min read

HPLC-grade water does not adequately separate trace compounds in chromatography experiments.

Remove a Common Source of Experimental Error

Reducing Risk in Therapeutic Drug Treatment and Monitoring

ELGA Veolia | Nov 4, 2021 | 1 min read

A simple solution to contaminated water affecting HPLC and LC-MS/MS experiments.

Measuring Metabolites to Prevent, Diagnose, and Treat Cancer

Niki Spahich, PhD | Jun 11, 2021 | 1 min read

Metabolomics research highlights molecules important for cancer prevention, diagnosis, and treatment.

The Community-Wide Effort to Standardize QA/QC for Metabolomics and Lipidomics

The Scientist | Apr 27, 2021 | 1 min read

Perspectives on the basics and future of QA/QC

Lipids in the Spotlight

Carina Storrs | Aug 1, 2012 | 8 min read

A guide to studying lipids using mass spectrometry