Prenatal Inflammation Makes Mice Susceptible to Asthma
Prenatal Inflammation Makes Mice Susceptible to Asthma
Maternal immune responses during mice gestation led to a hyperactive population of innate-like immune cells in offspring that contributed to altered lung composition and function.
Maternal immune responses during mice gestation led to a hyperactive population of innate-like immune cells in offspring that contributed to altered lung composition and function.
inflammation
A Better Mucus Model
Aparna Nathan, PhD | Aug 20, 2024 | 4 min read
A more realistic model of the mucus layer that lines the lungs and gut could provide important insights into the function of this critical defensive barrier.
How Exercise Sparks, then Soothes, Inflammation
Rachael Moeller Gorman | May 15, 2024 | 4 min read
Regulatory T cells in muscles surge after exercise, quelling inflammation, protecting mitochondria, and enhancing performance.
Aging and Cancer
Rebecca Roberts, PhD | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms.
Cell Surface RNA Helps Neutrophils Get Around
Holly Barker, PhD | Apr 2, 2024 | 4 min read
A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.
Bat Immune Systems: The Original Antivirus Programs
Hannah Thomasy, PhD | Mar 15, 2024 | 3 min read
Bats stay healthy while hosting some of the world’s deadliest viruses. Scientists are just beginning to understand how.
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
Fighting Cancer: Lessons from the Naked Mole-rat
Hannah Thomasy, PhD | Dec 1, 2023 | 2 min read
Mice live longer, healthier lives thanks to a gene from their glabrous subterranean cousins.
Infographic: Capturing a More Complete Picture of Expression
Deanna MacNeil, PhD | Jun 1, 2023 | 1 min read
CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging
The Scientist | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline.
Vaccines: Sex Matters
Niki Spahich, PhD | Jun 1, 2023 | 3 min read
Male patients who recover from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges than female patients.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Science Philosophy in a Flash - A Look at Aging Through Young Eyes
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
How Cells in the Skin Team Up To Fight Pathogens
Rachael Moeller Gorman | Apr 12, 2023 | 4 min read
Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist and MilliporeSigma | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
SARS-CoV-2 Infection Can Alter Future Immune Reponses
Niki Spahich, PhD | Feb 22, 2023 | 3 min read
Males recovered from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges.
Connecting the Complexities of Heart Failure and Aging
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers learned how IGFBP7, a senescence signaling protein and biomarker, promotes cardiac remodeling and cellular aging.
The Next Generation of Immunoassays Support COVID-19 Research
The Scientist Creative Services Team in collaboration with Bio-Techne | 3 min read
An automated, microfluidic immunoassay system enables researchers to quickly and reliably measure cytokines in patient blood samples.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment
Deanna MacNeil, PhD | Jan 23, 2023 | 3 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.