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Cartoon of a human brain made from puzzle pieces, with some pieces not in place.
Charting a New Course Through the Injured Brain
A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.
Charting a New Course Through the Injured Brain
Charting a New Course Through the Injured Brain

A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.

A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.

in situ hybridization

In situ hybridization procedure being conducted in a laboratory.
Tips and Tricks for In Situ Hybridization
Priyom Bose, PhD | Jun 11, 2024 | 8 min read
In situ hybridization is a powerful molecular technique for detecting and localizing specific nucleic acids in cytological samples. 
Discover how to capture whole transcriptome expression in FFPE samples.
Uncover Archived Expression Profiles in FFPE Samples
10x Genomics | Jun 22, 2023 | 1 min read
Researchers can overcome RNA degradation challenges in preserved samples with an in situ hybridization-based single cell expression profiling assay.
Learn about spatial biology techniques modernizing biological research
Advancing Spatial Biology Technology
10x Genomics | Mar 28, 2023 | 1 min read
How spatial biology techniques evolved over time 
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Technique Talk: Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
The Scientist | Oct 21, 2022 | 1 min read
In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist and Resolve Biosciences | Apr 12, 2022 | 1 min read
How to visualize gene expression patterns in situ
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Using Digital Spatial Profiling for Transcriptomic Analysis of Neuronal Subpopulations
The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | Nov 12, 2021 | 1 min read
Kit Fuhrman and Anushka Dikshit present how to obtain whole transcriptome data from spatially mapped neuron populations.
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Studying Cellular Heterogeneity in the Lower Urinary Tract with Spatial Transcriptomics
The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | Aug 24, 2021 | 2 min read
Anushka Dikshit, Kit Fuhrman, and Diya Joseph present how to leverage in situ hybridization and spatial genomic profiling for prostate cancer research.
Spatial Profiling Immune Cells in Tumors
Spatial Profiling of Immune Signatures in the Tumor Microenvironment
Bio-Techne | Aug 17, 2021 | 1 min read
Explore an in situ transcriptomic approach for mapping target genes in heterogeneous tumor tissues.
Longitudinal Immune Profiling Reveals Key Immune Signatures Associated with COVID-19
The Scientist | Sep 14, 2020 | 1 min read
Madhvi Menon will discuss immune profiling of COVID-19 patients and Jyoti Phatak-Sheldon will highlight the use of RNAscope in situ hybridization in SARS-CoV-2 research.
In Situ Hybridization Explained
The Scientist | Nov 30, 2017 | 1 min read
Profilee Joseph Gall of the Carnegie Institute describes the process, which he developed in the 1960s.
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