immunology

Leishmania parasites often cause puzzlingly painless lesions. Scientists are beginning to dig into the mechanisms underlying this pain-blocking effect.

Vaccination through the eyes stimulated a protective response in the brains of mice, revealing an immunological link between these two organs.

Bacterial superorganisms must evolve defenses to fight off infections, and microbiologists found that they use a weapons cache coincidentally similar to that of the human immune system.

A transcription factor in mouse brains underpins stress, social behaviors, and possibly immunity.

To enter the nucleus, the HIV-1 virus acts like a transport receptor, which presents new targets for antiviral therapies.

Smoking leaves epigenetic marks on DNA long after cessation, with consequences for adaptive immunity.

Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.

A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.

In rats, motherhood leaves long-term biological signatures in a brain region that is crucial for learning and memory.

Some commensal bacteria help shore up intestinal walls in mice, which can prevent food allergies.

Influenza infection activates a pathway that leads to a detrimental drop in progesterone during pregnancy in mice.

Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.

The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.

Bats stay healthy while hosting some of the world’s deadliest viruses. Scientists are just beginning to understand how.