immune system

Some elements of human immune systems serve important functions beyond fighting infections.

Spectral flow cytometry separates similarly emitting fluorophores and enabled Kaitlyn Sadtler to construct a 24-color rat panel for immunological analyses.

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 

SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 

The “tripledemic” shines a spotlight on viral interference, in which one infection can block another.

Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.

Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.

IgA antibodies appear to bind to specific species of commensal gut bacteria in mice, according to a study.

Several lines of evidence suggest that targeting the body’s defense pathways might help treat a subset of people with the psychiatric disorder. But many open questions remain.

Scientists have pinpointed several pathways through which the immune system could disrupt neuronal functioning and thereby lead to psychotic symptoms.

Two recent papers provide insight into possible risk factors for developing the chronic condition, including autoantibodies and diabetes.

Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.