immune cells

Clean and dirty mice respond similarly to allergens, challenging the idea that reduced microbial exposure is the primary cause behind the uptick in allergies.

Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease. 

Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.

A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.

Dialing up the activity of a protein called SYK in the brain’s “janitors” could provide an avenue to treat Alzheimer’s and other neurodegenerative diseases.

Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.

Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home.

Bats are known for staying healthy even while harboring viral infections. Now, research sheds light on how their unusual immune system evolved.

Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.

Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 

The ability to activate different sets of genes has likely helped the chytrid fungus Batrachochytrium dendrobatidis spread widely in amphibians, resulting in global population declines.