HIV

A host lipid-modifying enzyme plays a key role in HIV envelope formation, viral maturation, and infectivity. 

From development to implementation, Rosanna Peeling discusses the importance of rapid tests for public health.

Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice. 

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.

CRISPR-mediated removal of HIV can create small, infectious DNA molecules.

Umbilical cord blood may be a good alternative to bone marrow transplants for treating HIV in patients with HIV and cancer.

The Nobel laureate had courted controversy in recent years on vaccines and other matters.

Overbearing restrictions on research into toxins and pathogens such as SARS-CoV-2 could undermine public health and security in the long run.

As the year draws to a close, we look back on researchers we bid farewell to, and the contributions they made to their respective fields.

Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.

Transplanted CAR stem cells persisted long term and showed multilineage engraftment in tissues that harbor HIV.

Engineered viruses that don’t replicate provide a tractable model for scientists to safely study SARS-CoV-2, including research into vaccine efficacy and emerging variants.