GPCR

Researchers simulated interactions between microbial molecules and neural receptors to explore whether gut bacteria might influence brain chemistry.

Scientists compared protein engineering with a synthetic library versus error-prone PCR to achieve better variant representation and simpler validation.

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

Nobel laureate Alfred Gilman has passed away at age 74.

Novel microfluidic devices give researchers new ways to count and sort single cells.

Scientists create a photosensitive pharmaceutical to target a glutamate receptor.

Researchers are beginning to study in depth the largely uncharted territory of the eye’s microbial composition.

The challenges of crystallizing membrane proteins—and how they’re being overcome.

Editor's choice in drug discovery