Ancient Alleles Shed Light on Atherosclerosis Risk
Calculating the polygenic risk scores of ancient humans such as Ötzi the iceman helps researchers understand the genetic predisposition to cardiovascular disease.
Ancient Alleles Shed Light on Atherosclerosis Risk
Ancient Alleles Shed Light on Atherosclerosis Risk
Calculating the polygenic risk scores of ancient humans such as Ötzi the iceman helps researchers understand the genetic predisposition to cardiovascular disease.
Calculating the polygenic risk scores of ancient humans such as Ötzi the iceman helps researchers understand the genetic predisposition to cardiovascular disease.
Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.