genetics
Automating In Vivo Screens and Challenging Dogma
Deanna MacNeil, PhD | Jun 19, 2024 | 3 min read
Scientists built a microfluidic lab-on-a-chip device that accelerates compound screens and phenotype analyses in C. elegans models of reproductive aging.
Building Cells from the Bottom Up
Danielle Gerhard, PhD | Jun 14, 2024 | 8 min read
To understand the molecular blueprint for life, Cees Dekker is starting from scratch, building fully synthetic cells that are capable of cell division.
The Promise and Power of Pharmacogenomics
Thermo Fisher Scientific | 1 min read
Technological advances and high throughput techniques offer scientists speed and scalability in precision medicine research and applications.
Herding Innovation in Livestock
Laura Tran, PhD | Jun 14, 2024 | 9 min read
Alison Van Eenennaam uses genome-editing technologies to aid beef cattle production and animal welfare.
Discovering the Functions of Noncoding Sequence Variants
Niki Spahich, PhD | Jun 12, 2024 | 4 min read
Neville Sanjana explored noncoding genomic regions by combining pooled CRISPR screening and single cell sequencing.
Enhancing Efficiency in the Clinical Research Laboratory
Thermo Fisher Scientific and The Scientist | 1 min read
Automation, multiplexing, artificial intelligence, and more come together to build a better laboratory environment.
Artificial Chromosomes for Disease Modeling
Holly Barker, PhD | Jun 12, 2024 | 3 min read
A new technique for synthesizing chromosomes can introduce panels of genes into disease models to facilitate drug testing.
Boosting Bacterial Genomes to Better Explore the Microbiome
Aparna Nathan, PhD | Jun 7, 2024 | 4 min read
Gang Fang’s new metagenomics method helps sequence rare bacteria.
Tips and Tricks for In Situ Hybridization
Priyom Bose, PhD | 8 min read
In situ hybridization is a powerful molecular technique for detecting and localizing specific nucleic acids in cytological samples.
Human Neurons Play the Waiting Game
Shelby Bradford, PhD | Jun 5, 2024 | 4 min read
When it comes to development, an epigenetic clock may be responsible for human neurons’ slower maturation.
Cracking the Color Cone-undrum in Human Vision
Laura Tran, PhD | Jun 3, 2024 | 2 min read
Cell color perception fates are determined by a signaling mechanism, not chance, during retinal development.
Harnessing Metagenomics for Health and Disease Research
The Scientist Staff | 1 min read
Discover how metagenomics approaches provide insights into human diseases.
Bioengineering Interkingdom Communication
Hannah Thomasy, PhD | Jun 3, 2024 | 2 min read
Genetically edited bacteria sense the environment and report their findings to “listening” plants.
The Nucleus’ Secret to Shapeshifting
Kamal Nahas, PhD | May 31, 2024 | 4 min read
Neutrophils contort their nuclei into various shapes by moderating one key regulatory protein previously shown to orchestrate DNA organization.
Understanding the Effects of Extrachromosomal DNA on Cancer
The Scientist | 1 min read
Lukas Chavez uses multiomic techniques to study how extrachromosomal DNA (ecDNA) contributes to tumor heterogeneity and gene expression changes in medulloblastoma.
Centromeres Mutate More Rapidly Than Expected
Kamal Nahas, PhD | May 30, 2024 | 4 min read
After sequencing centromeres in humans and other primates, researchers found that they vary greatly across species and potentially contribute to aging and disease.
With Neither Brains nor Brawn, Jellyfish and Relatives Developed Subcellular Weapons Instead
Hannah Thomasy, PhD | May 29, 2024 | 6 min read
Anna Klompen explained how cnidarian stinging cells harpooned their way into her heart and could help answer fundamental questions in biology.
DNA Barcoding: Species Detection and High Throughput Assays
Priyom Bose, PhD | 7 min read
DNA barcoding is a fast sequencing-based technique that scientists use to catalog all life on Earth or perform high throughput bioanalyses.
Obesity Research is Going to the Dogs
Hannah Thomasy, PhD | May 27, 2024 | 5 min read
Gene mutations in rotund retrievers shed light on the neural regulation of body weight.
Using Genetic Cartography to Map Cell Lineage
Laura Tran, PhD | May 17, 2024 | 4 min read
By coupling cell lineage tracking with molecular gene expression patterns, researchers deciphered how gene activity influences immune cell production.