gene editing

A new approach using two types of recombinases lets scientists insert larger DNA payloads into human pluripotent stem cells faster than ever before. 

Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.

Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.

Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.

CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.

Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.

By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.

New research may make immunotherapy possible for hard-to-treat brain tumors.

In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.

In both the laboratory and clinic, scientists harness viral genetic transfer capabilities to develop gene therapies that modulate cellular function.

Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.

A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?

Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.