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Pseudo-colored scanning electron microscope image of the algae microrobot with the algae in green and the drug-filled nanoparticles in orange.
Green Warriors: Algae Microrobots Set to Combat Metastasis
Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.
Green Warriors: Algae Microrobots Set to Combat Metastasis
Green Warriors: Algae Microrobots Set to Combat Metastasis

Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.

Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.

drug delivery

Image shows photorhabdus virulence cassettes (green) binding to insect cells (blue) prior to injection of payload proteins. 
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells
Rohini Subrahmanyam, PhD | Apr 20, 2023 | 4 min read
Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.
Structure of a Chlamydomonas, green algae
Drugs Hitch a Ride on Algae for Targeted Delivery
Holly Barker, PhD | Feb 1, 2023 | 3 min read
A new microrobot uses algae to transport antibiotics into the lungs of mice with pneumonia.
From the Expert: Click Chemistry and Bioorthogonal Applications
From the Expert: Click Chemistry and Bioorthogonal Applications
The Scientist | 1 min read
Carolyn Bertozzi discusses her recent work on targeted degradation therapies that rely on bioorthogonal chemistry.
Illustration showing microscopic algae swim through mouse lungs and deliver nanoparticles of an antibiotic attached to their surfaces
Infographic: Algae Robots Transport Antibiotics to Infected Tissues
Holly Barker, PhD | Feb 1, 2023 | 1 min read
Microscopic algae dotted with drug-filled nanoparticles may offer a more effective means of treatment than traditional delivery methods.
Lipid nanoparticle delivers treatment to a cancer cell.
Researchers Develop a CRISPR-Based Therapy That Penetrates Solid Tumors
Jennifer Zieba, PhD | Oct 10, 2022 | 3 min read
By packaging lipid nanoparticles with elements that decrease the fibrous nature of solid tumors, researchers can deliver CRISPR therapies in a more efficient manner.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
A microneedle patch on a fingertip
Opinion: An Alternative to Injection
Carmine D’Amico and Hélder Santos | Sep 9, 2021 | 3 min read
Research on microneedle patches for vaccine delivery has grown in popularity in recent years, due to their exceptional compliance and low invasiveness.
Building a Synthetic Biology Platform for Drug Delivery
Building a Synthetic Biology Platform for Drug Delivery
The Scientist | 1 min read
Kate Adamala and Niren Murthy will discuss the latest advances in drug delivery using synthetic biology approaches.
Red blood vessels that decrease in diameter as they radiate outward are pictured on a pink and white surface
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD | Aug 18, 2021 | 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
Questions Raised About Widely Used Blood-Brain Barrier Model
Catherine Offord | Feb 16, 2021 | 6 min read
A study has sparked controversy by suggesting that cells made using a popular lab protocol have been misidentified, with potentially serious repercussions for brain research. Critics say the significance of the findings has been overstated.
Linking Biological Clocks and Cancer Therapeutics to Minimize Toxicity
It’s All in the Timing: Optimizing Chemotherapy Administration
Sejal Davla, PhD | 1 min read
How the biological clock influences chemotherapy success
Infographic: Building Bacteria to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 3 min read
Researchers are engineering microbes to deliver therapeutics specifically to tumors, maximizing the treatments’ efficacy while minimizing side effects.
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Harnessing microRNAs for Cancer Therapeutics
Harnessing microRNAs for Cancer Therapeutics
The Scientist | 1 min read
Andrea Kasinski and Masako Harada will discuss the role of microRNAs in cancer, as well as the potential and challenges of using microRNAs for cancer therapeutics.
Laser-Triggered Nanobubbles Blast a Path into Biofilms
Jonathan Wosen | Apr 1, 2020 | 4 min read
Researchers could one day use the method to deliver antibiotics to topical wounds infected by hard-to-treat masses of bacteria.
CRISPR-Based Tool Expands DNA-Hydrogel Versatility
Ruth Williams | Dec 1, 2019 | 3 min read
DNA-responsive polymer gels used for releasing drugs, encapsulating cells, and much more now have greater adaptability thanks to the Cas12a nuclease.
Trial of Gene Therapy for Duchenne Muscular Dystrophy Put on Hold
Catherine Offord | Nov 12, 2019 | 2 min read
The US Food and Drug Administration halts a study by Solid Biosciences after a patient experiences severe side effects following treatment.
smartphone controlled device implanted in mouse brain
Image of the Day: Smartphone-Controlled Brains
Nicoletta Lanese | Aug 7, 2019 | 1 min read
A device implanted into mice can modulate brain circuit activity over long periods of time.
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