drosophila

A neuropeptide suppressed feeding in two evolutionarily distant species, suggesting that hunger regulation may go back to the roots of the tree of life.

A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.

The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick.

A new algorithm scrutinizes the most hard-to-read segments of the genome.

For decades, Matthews led two important repositories for fruit fly research: the Bloomington Drosophila Stock Center and FlyBase.  

In Drosophila, the tissue is more permeable to drugs at night, offering a possible explanation for why some medicines work better at certain times of day.

Previously considered immobile, these cells swoop in to seal epithelial holes and clean up cellular detritus.  

Researchers examine the effects on the fruit fly intestine of the protein responsible for Fragile X syndrome in humans. 

In Drosophila larvae, the formation of blood cells takes place in a specialized organ, the lymph gland.

Young talks with The Scientist about studying circadian rhythms in fruit flies, the applications of his work beyond Drosophila, and winning the prize. 

A basic curiosity about how life works led the Brandeis University molecular biologist to discover how our bodies keep time. 

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

Phosphorylation of a surface protein on endosomes is key to the organelles’ uneven distribution in daughter cells.

Phosphorylation of a protein called Sara found on the surface of endosomes appears to be a key regulator of asymmetric splitting in fruit flies.

E. coli that make indoles protect older worms, flies, and mice from frailty. 

Surrounded by a projection screen, a fly’s flight path is influenced by a collection of moving dots.

Experiments that place untethered fish, flies, and mice in simulated environments give clues about the animals’ social behavior.

The protein encoded by the gene that causes Fragile X in humans partners with another protein, dNab2, to alter gene expression in fruit fly neurons.

Ribosome-inactivating proteins from symbiotic bacteria leave their hosts unharmed.