DNA

A new approach using two types of recombinases lets scientists insert larger DNA payloads into human pluripotent stem cells faster than ever before. 

A new technique for synthesizing chromosomes can introduce panels of genes into disease models to facilitate drug testing.

A receptor that recognizes DNA fragments formed during learning is necessary for proper memory formation.

An advanced multiomics solution allows researchers to predict gene expression, chromatin accessibility, and enhancer state from one DNA sample.

A common mistake and a well intentioned but misguided gesture led Allison Mackay’s experiment awry in the lab.

A rapid isothermal amplification technique enables pathogen identification and antibiotic resistance detection in low-resource settings.

Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.

Samantha Maragh has taken on the difficult challenge of standardizing assays, data norms, and terminology in the ever evolving genome editing field.

Natalie Knox and the Public Health Agency of Canada’s National Microbiology Laboratory are helping establish a national qPCR-driven wastewater surveillance network for SARS-CoV-2 and other diseases.

For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.

Lasker Award winner Evelyn Witkin discovered the mechanism for DNA repair following UV damage.

Endonuclease R changed Richard Roberts’ career trajectory and created an industry.

Researchers identify hundreds of candidate histone proteins in bacteria, including one with an unusual way of binding to DNA.