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Cuboidal DNA origami block containing parallel double helices (gray columns) decorated with tumor antigens (green proteins) and CpG adjuvants (yellow helices) on opposing faces.
Fighting Tumors with DNA Origami
Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.
Fighting Tumors with DNA Origami
Fighting Tumors with DNA Origami

Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.

Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.

DNA origami

Building Nerf Gun Blasters from DNA Bricks
Laura Tran, PhD | Jan 11, 2024 | 3 min read
Researchers ingeniously repurposed DNA to assemble a miniaturized blaster at the molecular level.
A syringe delivering a fleet of DNA nanorobots to a cancer cell.
Building Biomolecular Machines
Danielle Gerhard, PhD | Jan 1, 2024 | 2 min read
William Shih draws inspiration from origami and jigsaw puzzles in his quest to build bigger DNA nanorobots.
Yellow smiley faces on a black background
Coming Into the Fold: DNA Origami
Danielle Gerhard, PhD | Dec 4, 2023 | 9 min read
In 2006, Paul Rothemund transformed the field of DNA nanotechnology when he unveiled an innovative approach for making shapes and patterns from genetic material.
An artist’s rendering of a DNA-based virus trap, represented as gray rods in a short cone-shaped arrangement. One is coated with blue molecules, likely antibodies, that adhere to a virus target. Another image shows to traps coming together to capture a red coronavirus.
“Origami” DNA Traps Could Keep Large Viruses From Infecting Cells
Natalia Mesa, PhD | Jan 18, 2023 | 4 min read
By engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.
Caught on Camera
The Scientist | Apr 1, 2018 | 2 min read
Selected Images of the Day from the-scientist.com
DNA Robots Target Cancer
Abby Olena, PhD | Feb 12, 2018 | 2 min read
Researchers use DNA origami to generate tiny mechanical devices that deliver a drug that cuts off the blood supply to tumors in mice.
Top Technical Advances in 2017
Shawna Williams | Dec 24, 2017 | 3 min read
The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.
The Biggest DNA Origami Structures Yet
Abby Olena, PhD | Dec 6, 2017 | 3 min read
Three new strategies for using DNA to generate large, self-assembling shapes create everything from a nanoscale teddy bear to a nanoscale Mona Lisa.
Cargo-Sorting DNA Robots
Ruth Williams | Sep 14, 2017 | 3 min read
Autonomous molecules that collect, carry, and sort different genetic packages usher in a new era for nucleic-acid robotics. 
Twists and Turns
Mary Beth Aberlin | Jul 16, 2017 | 3 min read
New starring roles for nucleic acids
Contributors
The Scientist | Jul 16, 2017 | 3 min read
Meet some of the people featured in the July/August issue of The Scientist.
Building Nanoscale Structures with DNA
Arun Richard Chandrasekaran | Jul 16, 2017 | 10+ min read
The versatility of geometric shapes made from the nucleic acid are proving useful in a wide variety of fields from molecular computation to biology to medicine.
DNA Origami
The Scientist | Jul 16, 2017 | 1 min read
Will complex, folded synthetic DNA molecules one day serve as capsules to deliver drugs to cancer cells?
More-Stable DNA Origami
Tracy Vence | Jul 23, 2015 | 1 min read
Scientists build nanoscale mesh models of a rabbit and a human stick figure, among other things. 
Giant DNA Origami
Jef Akst | Sep 18, 2014 | 2 min read
Researchers create the largest 3-D DNA structures to date, many times bigger than previously constructed origami shapes.
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