disease model
Major Advances in Mini Brain Bioengineering
The Scientist | Mar 31, 2023 | 1 min read
Explore the latest developments in brain organoid production.
Male and Female Stem Cells Derived from One Donor in Scientific First
Dan Robitzski | Dec 22, 2022 | 3 min read
Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth.
Studying Organ Development and Disease Using Organoids
The Scientist Staff | 1 min read
In this symposium, an expert panel will discuss how cutting-edge organoid research lends insights into normal development and shows what happens when processes go awry.
Climate Change, Deforestation Drive Bat Virus Spillover Into Humans
Amanda Heidt | Nov 17, 2022 | 4 min read
Bats that experience food shortages due to climate change and habitat loss end up roosting in urban settings, where they shed more of the deadly Hendra virus.
Colin Carlson Works to Predict and Prevent Viral Spillover
Catherine Offord | Jul 18, 2022 | 3 min read
The Georgetown University biologist studies how climate change contributes to the emergence of new zoonotic threats.
New Strategies to Discover Human Disease Genes
The Scientist | 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
Vaccine Exemptions May Allow for Large Measles Outbreaks
Abby Olena, PhD | Aug 21, 2019 | 4 min read
Mathematical models reveal that current vaccination rates in Texas schools could pave the way for the virus to spread to hundreds of people.
First Genetic Screen of Pigs Using ENU
Ashley Yeager | Jul 14, 2017 | 3 min read
Using the mutagenic chemical N-ethyl-N-nitrosourea, researchers confirm the role of a gene in a piglet deformity and identify potential models for human diseases.
Modeling Human Disease and Development with Organoids
The Scientist | 1 min read
Discover how scientists use cardiac and skin organoids to study differentiation and toxicity.
Image of the Day: Imitation Intestines
The Scientist | Mar 12, 2017 | 1 min read
This 3-D model of human intestinal cells could help scientists develop new antimicrobial drugs and therapeutics.
Predicting Zika’s Potential Path
Bob Grant | Mar 17, 2016 | 2 min read
The mosquitoes that carry the virus could spread to US cities this summer, with travelers returning from Zika-infected regions contributing to the disease’s spread.
Leveraging Stem Cells to Create Better Disease Models
The Scientist | 2 min read
Clive Svendsen, Meritxell Huch, Ameen Salahudeen, and Maksim Plikus will discuss the latest advances in using patient-derived stem cells to create more accurate disease models.
Opinion: New Models for ASDs
Alysson R. Muotri | May 13, 2015 | 3 min read
The study of mini “brains” in a dish, derived from patient cells, offers a novel approach for autism spectrum disorder research.
Organoid Biobank
Kerry Grens | May 11, 2015 | 2 min read
From the tissue of numerous colon cancer patients, researchers build 3-D cultures of tumors.
Generating Mini-Guts for Drug Screening
The Scientist and MilliporeSigma | 4 min read
Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts.
Homo Minutus
Jyoti Madhusoodanan | Dec 1, 2014 | 4 min read
A miniature platform with multiple organ-on-a-chip constructs aims to speed up drug discovery—and create better transplants for patients.
Desktop Human
Jyoti Madhusoodanan | Nov 30, 2014 | 1 min read
Meet the researchers behind ATHENA, the project that aims to create a system of linked model human organs that may revolutionize drug development.
Technique Talk: Induced Pluripotent Stem Cells: Reprogramming and Applications
The Scientist | 1 min read
Ritu Kumar will discuss how derivation of induced pluripotent stem cells from somatic cells has revolutionized regenerative medicine.
Diseased Heart Chip
Jef Akst | May 12, 2014 | 2 min read
In the latest iteration of organ-on-a-chip technology, researchers develop an in vitro model of functioning human heart tissue with an inherited cardiovascular disease.