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A cartoon of a woman highlights her large and small intestines with depictions of bacteria comprising the gut microbiota.
Linking Fasting to Health and the Gut Microbiome
Alex Mohr discusses a trial comparing various calorie-restricted diets on the gut microbiome and overall health measures.
Linking Fasting to Health and the Gut Microbiome
Linking Fasting to Health and the Gut Microbiome

Alex Mohr discusses a trial comparing various calorie-restricted diets on the gut microbiome and overall health measures.

Alex Mohr discusses a trial comparing various calorie-restricted diets on the gut microbiome and overall health measures.

dietary restriction

Photo of several diet foods
Book Excerpt from Anxious Eaters: Why We Fall for Fad Diets
Janet Chrzan and Kima Cargill | Jul 25, 2022 | 5 min read
In Chapter 1, “Why We Love Fad Diets,” authors Janet Chrzan and Kima Cargill explain the American propensity to take shortcuts to weight loss.
Photo of several diet foods
Opinion: Why We Fall for Fad Diets
Janet Chrzan | Jul 18, 2022 | 5 min read
Human beings are susceptible to the latest nutritional trends, regardless of their actual biological value.
A photo of a triple-negative breast cancer cell
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Devin A. Reese, PhD | Mar 1, 2022 | 2 min read
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
illustration of inside of human chest with highlighted gland between the lungs
Genetically Altered Mice Harness Benefits of Calorie Restriction  
Sophie Fessl, PhD | Feb 11, 2022 | 4 min read
A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.
Artist's impression of the human microbiome
Diet Implicated in Autism-Microbiome Link
Ruth Williams | Nov 11, 2021 | 3 min read
The unbalanced gut flora present in some people with autism is not a driver of the condition but rather a consequence of eating behaviors characteristic of the condition, a new study claims.
Could Grandpa’s Early Diet Affect Your Health?
Shawna Williams | Apr 1, 2019 | 4 min read
A large study seeks to answer whether a man’s childhood diet has transgenerational repercussions.
Researchers Explore the Genetics of Eating Disorders
Amy Lewis | Jan 1, 2019 | 4 min read
Large-scale genomic studies of anorexia and bulimia are turning up clues about the conditions’ development and persistence.
Caloric Restriction Slows Signs of Aging in Humans
Diana Kwon | Mar 26, 2018 | 2 min read
Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.
Mitochondrial Networks Explain Why Caloric Restriction Extends Worms’ Lives
Jef Akst | Nov 7, 2017 | 2 min read
Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.
Study: Eating Less Helps Worms Learn
Aggie Mika | Aug 2, 2017 | 2 min read
Food restriction decreases a metabolite that impedes associative learning in worms. 
Running on Empty
Bob Grant | Jun 1, 2017 | 10+ min read
Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.
Growth Hormone Guidance
Jenny Rood | Mar 1, 2015 | 2 min read
Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.
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