cancer

An artistic illustration of the female reproductive system.

Mariella Bodemeier Loayza Careaga, PhD | May 8, 2024 | 4 min read

Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process.

Two cells fluorescently stained for normal (red) and damaged (green) lysosomes.

Cancer Cells Spread When They Stop Recycling Waste

Kamal Nahas, PhD | May 8, 2024 | 4 min read

An immune-inhibiting protein that regulates autophagy halts breast cancers from venturing across tissue borders.

Optimers Bring Precision to Cancer Research and Therapeutics

The Scientist Staff | 1 min read

In this webinar, David Bunka will discuss how scientists can use Optimer® binders in cancer research.

Cuboidal DNA origami block containing parallel double helices (gray columns) decorated with tumor antigens (green proteins) and CpG adjuvants (yellow helices) on opposing faces.

Fighting Tumors with DNA Origami

Kamal Nahas, PhD | May 6, 2024 | 5 min read

Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.

Close-up painting of hands drawing the DNA helix.

Measuring Mutagenesis with Precision Genome Editing

Deanna MacNeil, PhD | May 3, 2024 | 5 min read

A new prime editing sensor library targeting p53 mutations allowed scientists to interrogate thousands of tumor genotypes as they arose in endogenous contexts.

Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution

The Scientist Staff | 1 min read

In this webinar, Matthias Brendel will discuss a new PET approach called scRadiotracing, which involves immunomagnetic cell sorting after in vivo radiotracer injection combined with 3D histology.

Translating ctDNA Detection into Breast Cancer Research Breakthroughs

The Scientist Staff | May 1, 2024 | 2 min read

Noninvasive methods to monitor traces of cancer left over after treatment may lead to better early interventions.

A microscopy image stained for different cell populations in breast tumors.

Cancer Cells Give Orders

Holly Barker, PhD | Apr 23, 2024 | 4 min read

Cancer-supporting cells control their neighbors’ behavior using an often-overlooked protein delivery system.

New Research Avenues Provide Hope for Metastatic Disease

The Scientist Staff | 2 min read

Learn about the latest cellular studies that help researchers discover the mechanisms of cancer metastasis.

A scanned image of stained mouse pulmonary tissue.

Lung Cancer Cells Switch Oncogenic Drivers

Alejandra Manjarrez, PhD | Apr 23, 2024 | 3 min read

Mouse models mimicking the transition from a common form of lung cancer to a more aggressive one may help scientists develop future strategies to prevent this transformation.

Keeping Telomeres in Their Places

Aparna Nathan, PhD | Apr 22, 2024 | 4 min read

New research reveals how cells prevent telomerase from meddling with double-stranded breaks.

Tapping into Immunotherapy’s Potential to Help More People

The Scientist Staff | 2 min read

Discover what researchers have learned about varying immunotherapy response rates between patients with the same cancer types.

Conceptual illustration of personalized medicine with medical icons next to a human face.

The Largest Whole-genome Sequencing Study in Cancer

Danielle Gerhard, PhD | Apr 17, 2024 | 7 min read

Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.

Two sister cells are seen in the foreground, while individual cells are seen behind them on a blue background.

Sister Cells Reveal Cancer’s Fate

Aparna Nathan, PhD | Apr 3, 2024 | 4 min read

A new method traces treatment resistant cells and predicts drugs that can make them more susceptible to cancer therapy.

Defining the Triple Negative Breast Cancer Morpholome

The Scientist Staff | 1 min read

Learn how researchers take a phenotype-first approach to uncover hidden metastatic drivers at tissue and cellular levels.

Crystalline ball-and-stick model representation of a molecular structure.

Prioritizing PARylation in DNA Damage and Repair

The Scientist Staff | Apr 1, 2024 | 2 min read

Measuring cellular poly ADP-ribosylation can unlock new anticancer strategies and approaches.

An image of cells with the center stained green and some cells stained magenta over a black background.

Growing Milk-Secreting Mammary Organoids

Sneha Khedkar | Mar 29, 2024 | 3 min read

Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer.