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3D illustration of p53 bound to DNA
One Protein to Rule Them All
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
One Protein to Rule Them All
One Protein to Rule Them All

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

cancer biology

Green and brown illustration of cancer cells in front of a peach and yellow background.
Bacterial Tractor Beams Bring Radiation to Tumors
Rachael Moeller Gorman | Apr 17, 2023 | 3 min read
Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.
Histological stain of in blue, red, and green of tumor
Self-Charging Battery Battles Tumors in Mice
Natalia Mesa, PhD | Apr 4, 2023 | 3 min read
A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.
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Present Your Paper in The Scientist’s Journal Club
The Scientist Staff | 1 min read
Apply today to share your cutting-edge research in The Scientist’s Journal Club.
electron micrograph of grey cancer cell, with two red T cells stuck to the side
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Natalia Mesa, PhD | Mar 29, 2023 | 4 min read
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Microscopy image of blue stained cohesin proteins.
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer
Shafaq Zia | Mar 3, 2023 | 2 min read
Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 
Performing Metabolomic and Functional Proteomic Analyses on a Heterogenous Cancer Cell Population
The Scientist Creative Services Team in Collaboration with IsoPlexis | 2 min read
A tumor metabolome panel identifies altered cell states that lead to drug tolerance.
Histological image of ccRCC
Mutational Signature Indicates Risk of Kidney Cancer Recurrence
Holly Barker, PhD | Mar 1, 2023 | 2 min read
DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds.
Infographic showing transposable elements in cancer
Infographic: Transposable elements in cancer
Diana Kwon | Mar 1, 2023 | 1 min read
Jumping genes are let loose in cancerous cells, with multiple effects on cell health.
Mining Coding Regions with Whole-Exome Sequencing
The Scientist | 1 min read
Multiple next-generation sequencing (NGS) techniques offer insights into health and disease.
Artists' renditions of cancer cells and tRNA molecules superimposed over one another.
Long noncoding RNAs and Microproteins Can Spark Cancer—or Sometimes Squelch It
Rachael Moeller Gorman | Mar 1, 2023 | 10+ min read
Noncoding RNAs and microproteins, once considered genomic noise, are turning out to be critical to the progression of some types of cancer.
Portrait of Alex Muir
Alex Muir Explores Cancer Cells’ Menu
Natalia Mesa, PhD | Mar 1, 2023 | 3 min read
The University of Chicago cell biologist is studying how the nutrients available to cancers influence their growth. 
Investigating the Immune Response Using Advanced Flow Cytometry
The Scientist | 1 min read
Discover how researchers are using flow cytometry to delve into the inner workings of the immune life cycle!
Composite image showing genes radiating from tumor cells
Jumping Genes’ Role in Cancer
Diana Kwon | Mar 1, 2023 | 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Red T cell
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD | Feb 14, 2023 | 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
Revealing the Complexities of Cancer with Single-cell RNA Analysis
The Scientist | 1 min read
Download this eBook to learn how single-cell analysis identifies subpopulations of tumor cells!
A colored microscopy image of a dividing breast cancer cell
Transfer RNAs Have a Surprising Role in Breast Cancer Growth
Natalia Mesa, PhD | Jan 5, 2023 | 4 min read
A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.
A collection of images from previous neuroscience articles, including those of an octopus in a chamber, artistic renditions of a brain, brain scans, and an image of neural connections in vitro.
Our Favorite Neuroscience Stories of 2022
Dan Robitzski | Dec 28, 2022 | 4 min read
This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more.
Advancing Cancer Vaccines
The Scientist | 1 min read
Sartorius invites you to join them for an educational webinar.
A collection of images from prior stories, including illustrations of DNA, chromosomes, and various cells, microscopy images of cancer cells, and a photo of a mouse on a treadmill.
Our Favorite Cancer Stories of 2022
Dan Robitzski | Dec 27, 2022 | 4 min read
This year, cancer researchers uncovered a variety of ways that tumors can survive and spread, ranging from damaging their own DNA to exploiting the nearby microenvironment for nutrients.
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