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HSC and bone
Hematopoietic Stem Cells and Their Role in Development and Disease Therapy
Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis
Hematopoietic Stem Cells and Their Role in Development and Disease Therapy
Hematopoietic Stem Cells and Their Role in Development and Disease Therapy

Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis

Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis

Brush-up Summaries

Context Is Key: Unlocking Tissue Complexity with Spatial Biology
Context Is Key: Unlocking Tissue Complexity with Spatial Biology
Deanna MacNeil, PhD | Mar 13, 2023 | 4 min read
Scientists combine spatially resolved imaging analyses with cutting edge single cell techniques for greater insight into fundamental and disease relevant pathways.
Cellular Senescence: Why Do Cells Stop Dividing?
Cellular Senescence: Why Do Cells Stop Dividing?
Elina Kadriu | Feb 28, 2023 | 4 min read
Senescent cells undergo major morphological and metabolic changes when at the end of their lifespan. 
Programmed Cell Death: Mechanisms for Cellular Self-Destruction
Programmed Cell Death Pathways
Elina Kadriu | Feb 15, 2023 | 7 min read
Cells use a variety of programmed cell death mechanisms to maintain homeostasis through cellular self-destruction, including apoptosis, necroptosis, and pyroptosis.
Artificial Organs: Innovating to Replace Donors and Dialysis
Artificial Organs: Innovating to Replace Donors and Dialysis
Deanna MacNeil, PhD | Jan 20, 2023 | 6 min read
Scientists employ cutting edge tools and techniques to create artificial organs for research and disease therapeutics.
3D medical illustration of peripheral blood cells: a lymphocyte (left) and a monocyte (right) surrounded by red blood cells.
PBMCs: Mononucleated and Multipurposed
Deanna MacNeil, PhD | Dec 16, 2022 | 4 min read
Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine.
Neuronal network with electrical activity of neuron cells in 3D
How Do Neurons Work?
Jennifer Zieba, PhD | Dec 15, 2022 | 6 min read
Neurons transmit sensory and mechanical information across synapses and along axons throughout the body via chemical signals and electrical impulses.
A colorful bouquet of fruits and vegetables in a mesh canvas bag.
Beyond Individual Nutrients: Complex Diet and Cancer Connections
Deanna MacNeil, PhD | Dec 6, 2022 | 4 min read
Scientists develop cancer nutrition guidelines based on research examining how dietary patterns affect cancer risk and prevention.
Brush Up: Quorum Sensing in Bacteria and Beyond
Brush Up: Quorum Sensing in Bacteria and Beyond
Deanna MacNeil, PhD | Nov 1, 2022 | 4 min read
Microbes communicate with quorum sensing to coordinate their behavior in response to how many neighbors they have.
Tissue Engineering and Regenerative Medicine: A New Frontier in Repairing Organ Damage
Brush Up: Tissue Engineering and Regenerative Medicine
Jennifer Zieba, PhD | Oct 17, 2022 | 4 min read
A new frontier in repairing organ damage
Medical illustration depicting self-renewal of a single stem cell dividing into two identical cells.<br><br>
What Is Stemness and Pluripotency?
Deanna MacNeil, PhD | Sep 30, 2022 | 5 min read
Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery.
Chromatogram peaks of a DNA sequencing analysis.
Brush Up: What Is Bisulfite Sequencing and How Do Researchers Use It to Study DNA Methylation?
Deanna MacNeil, PhD | Sep 15, 2022 | 4 min read
Prior to DNA methylation sequencing, researchers treat their samples with sodium bisulfite to distinguish methylated cytosine from unmethylated cytosine.
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | Aug 31, 2022 | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Hematopoietic Stem Cells
Hematopoietic Stem Cells and Their Role in Development and Disease Therapy
Jennifer Zieba, PhD | Aug 24, 2022 | 5 min read
Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis
Mini organs in a dish
What Are Organoids and How Are They Made?
Jennifer Zieba, PhD | Aug 11, 2022 | 8 min read
Miniaturized, in vitro versions of organs provide insights into disease and development.
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